Search Results for: IFNGR2

Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
Novel CCT8 chaperonin containing TCP1 subunit 8
  • Prefoldin mediated transfer of substrate to CCT/TriC
  • Formation of tubulin folding intermediates by CCT/TriC
  • Folding of actin by CCT/TriC
  • Association of TriC/CCT with target proteins during biosynthesis
  • Association of TriC/CCT with target proteins during biosynthesis
  • BBSome-mediated cargo-targeting to cilium
  • Neutrophil degranulation
  • Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Novel GRIK1 glutamate ionotropic receptor kainate type subunit 1
  • Activation of Na-permeable kainate receptors
  • Activation of Ca-permeable Kainate Receptor
  • Glutamic acid
  • Butabarbital
  • Topiramate
  • Tezampanel
Novel HCRTR1 hypocretin receptor 1
  • Orexin and neuropeptides FF and QRFP bind to their respective receptors
  • G alpha (q) signalling events
  • Suvorexant
  • Lemborexant
  • Daridorexant
Novel HLCS holocarboxylase synthetase
  • Biotin transport and metabolism
  • Defective HLCS causes multiple carboxylase deficiency
  • Biotin
  • Holocarboxylase synthetase deficiency
ADIPOQ adiponectin, C1Q and collagen domain containing
  • AMPK inhibits chREBP transcriptional activation activity
  • Transcriptional regulation of white adipocyte differentiation
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Adiponectin deficiency
ANXA5 annexin A5
  • Platelet degranulation
  • Fluocinolone acetonide
  • L-Alpha-Glycerophosphorylserine
  • L-thioproline
  • K201 free base
  • sn-glycero-3-phosphoethanolamine
  • 1,4-Dideoxy-O2-Sulfo-Glucuronic Acid
  • N,O6-Disulfo-Glucosamine
  • 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid
  • Copper
BNIP3 BCL2 interacting protein 3
BRICD5 BRICHOS domain containing 5
BTNL8 butyrophilin like 8
  • Butyrophilin (BTN) family interactions
CAMK2D calcium/calmodulin dependent protein kinase II delta
  • CaMK IV-mediated phosphorylation of CREB
  • HSF1-dependent transactivation
  • Trafficking of AMPA receptors
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Ras activation upon Ca2+ influx through NMDA receptor
  • Phase 0 - rapid depolarisation
  • Ion homeostasis
  • RAF activation
  • RAF/MAP kinase cascade
  • Signaling by moderate kinase activity BRAF mutants
  • Signaling by BRAF and RAF1 fusions
  • Paradoxical activation of RAF signaling by kinase inactive BRAF
  • Interferon gamma signaling
  • Regulation of MECP2 expression and activity
  • Ion transport by P-type ATPases
  • Assembly and cell surface presentation of NMDA receptors
  • Negative regulation of NMDA receptor-mediated neuronal transmission
  • Long-term potentiation
  • Signaling downstream of RAS mutants
  • Signaling by RAF1 mutants
  • 2-[4-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]iminocyclohexa-2,5-dien-1-yl]acetonitrile
  • (3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE
  • Fostamatinib
CD302 CD302 molecule
CLDN19 claudin 19
  • Tight junction interactions
CLEC7A C-type lectin domain containing 7A
  • CLEC7A (Dectin-1) signaling
  • CLEC7A (Dectin-1) signaling
  • Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
CXCL9 C-X-C motif chemokine ligand 9
  • Chemokine receptors bind chemokines
  • G alpha (i) signalling events
DNAJA3 DnaJ heat shock protein family (Hsp40) member A3
EMP3 epithelial membrane protein 3 (MAM blood group)
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
  • Phosphate bond hydrolysis by NTPDase proteins
ERMP1 endoplasmic reticulum metallopeptidase 1
GIMAP5 GTPase, IMAP family member 5
IFNG interferon gamma
  • Interferon gamma signaling
  • Regulation of IFNG signaling
  • Regulation of IFNG signaling
  • RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
  • Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
  • IFNG signaling activates MAPKs
  • Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells)
  • Olsalazine
  • Glucosamine
  • VIR201
  • Fontolizumab
  • Foreskin fibroblast (neonatal)
  • Foreskin keratinocyte (neonatal)
  • Emapalumab
  • Graft-versus-host disease
  • Allograft rejection

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