| Novel |
FCGR2B
|
Fc gamma receptor IIb |
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
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- Etanercept
- Human immunoglobulin G
- Abciximab
- Tositumomab
- Alemtuzumab
- Antithymocyte immunoglobulin (rabbit)
- Palivizumab
- Daclizumab
- Bevacizumab
- Sarilumab
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- Systemic lupus erythematosus
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| Novel |
MPZ
|
myelin protein zero |
- EGR2 and SOX10-mediated initiation of Schwann cell myelination
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- Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
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ADCK5
|
aarF domain containing kinase 5 |
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AHCYL1
|
adenosylhomocysteinase like 1 |
- PLC beta mediated events
- DAG and IP3 signaling
- Role of phospholipids in phagocytosis
- FCERI mediated Ca+2 mobilization
- Regulation of insulin secretion
- VEGFR2 mediated cell proliferation
- Ion homeostasis
- Ion homeostasis
- CLEC7A (Dectin-1) induces NFAT activation
- FCGR3A-mediated IL10 synthesis
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
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BAG4
|
BAG cochaperone 4 |
- Regulation of HSF1-mediated heat shock response
- Signaling by FGFR1 in disease
- TNF signaling
- Signaling by plasma membrane FGFR1 fusions
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C22orf15
|
chromosome 22 open reading frame 15 |
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CISH
|
cytokine inducible SH2 containing protein |
- Interleukin-7 signaling
- Neddylation
- Growth hormone receptor signaling
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COMMD6
|
COMM domain containing 6 |
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CYP4F12
|
cytochrome P450 family 4 subfamily F member 12 |
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DNAJB4
|
DnaJ heat shock protein family (Hsp40) member B4 |
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FLNA
|
filamin A |
- Platelet degranulation
- GP1b-IX-V activation signalling
- Cell-extracellular matrix interactions
- RHO GTPases activate PAKs
- OAS antiviral response
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- FG syndrome (FGS); Opitz-Kaveggia syndrome
- Periventricular nodular heterotopia (PVNH)
- Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
- Fronto-Otopalatodigital Osteodysplasia, including: Otopalatodigital syndrome, type I; Otopalatodigital syndrome, type II; Melnick-Needles syndrome; Frontometaphyseal dysplasia
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KRT222
|
keratin 222 |
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LGALS7
|
galectin 7 |
- Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
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- Beta-D-Glucose
- beta-D-Galactosamine
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LGALS7B
|
galectin 7B |
- Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
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- Beta-D-Glucose
- beta-D-Galactosamine
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PPIB
|
peptidylprolyl isomerase B |
- Collagen biosynthesis and modifying enzymes
- SARS-CoV-1 activates/modulates innate immune responses
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- Proline
- 1,4-Dithiothreitol
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PRAP1
|
proline rich acidic protein 1 |
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RPA1
|
replication protein A1 |
- Translesion synthesis by REV1
- Recognition of DNA damage by PCNA-containing replication complex
- Translesion Synthesis by POLH
- Removal of the Flap Intermediate from the C-strand
- Activation of ATR in response to replication stress
- SUMOylation of DNA damage response and repair proteins
- Regulation of HSF1-mediated heat shock response
- HSF1 activation
- Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
- Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
- Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
- PCNA-Dependent Long Patch Base Excision Repair
- Translesion synthesis by POLK
- Translesion synthesis by POLI
- Termination of translesion DNA synthesis
- HDR through Single Strand Annealing (SSA)
- HDR through Homologous Recombination (HRR)
- Processing of DNA double-strand break ends
- Presynaptic phase of homologous DNA pairing and strand exchange
- Formation of Incision Complex in GG-NER
- Gap-filling DNA repair synthesis and ligation in GG-NER
- Dual Incision in GG-NER
- Dual incision in TC-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- Fanconi Anemia Pathway
- Regulation of TP53 Activity through Phosphorylation
- Activation of the pre-replicative complex
- Removal of the Flap Intermediate
- G2/M DNA damage checkpoint
- Meiotic recombination
- Impaired BRCA2 binding to RAD51
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SNCA
|
synuclein alpha |
- Amyloid fiber formation
- PKR-mediated signaling
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- Resveratrol
- Dequalinium
- Copper
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- Lewy body dementia (LBD); Dementia with Lewy bodies (DLB)
- Parkinson's disease (PD)
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TERF1
|
telomeric repeat binding factor 1 |
- Recognition and association of DNA glycosylase with site containing an affected pyrimidine
- Cleavage of the damaged pyrimidine
- Recognition and association of DNA glycosylase with site containing an affected purine
- Recognition and association of DNA glycosylase with site containing an affected purine
- Cleavage of the damaged purine
- Cleavage of the damaged purine
- Meiotic synapsis
- Packaging Of Telomere Ends
- Telomere Extension By Telomerase
- Polymerase switching on the C-strand of the telomere
- Processive synthesis on the C-strand of the telomere
- Telomere C-strand (Lagging Strand) Synthesis
- Telomere C-strand synthesis initiation
- Removal of the Flap Intermediate from the C-strand
- DNA Damage/Telomere Stress Induced Senescence
- Inhibition of DNA recombination at telomere
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WEE2-AS1
|
WEE2 antisense RNA 1 |
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