| Novel |
ATP10A
|
ATPase phospholipid transporting 10A (putative) |
- Ion transport by P-type ATPases
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| Novel |
CD79B
|
CD79b molecule |
- CD22 mediated BCR regulation
- Potential therapeutics for SARS
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
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- Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
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| Novel |
CDK3
|
cyclin dependent kinase 3 |
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| Novel |
FBXO22
|
F-box protein 22 |
- Neddylation
- Antigen processing: Ubiquitination & Proteasome degradation
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| Novel |
FKBP1A
|
FKBP prolyl isomerase 1A |
- mTORC1-mediated signalling
- Calcineurin activates NFAT
- Calcineurin activates NFAT
- TGF-beta receptor signaling activates SMADs
- TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
- TGFBR1 LBD Mutants in Cancer
- Potential therapeutics for SARS
- SARS-CoV-1 activates/modulates innate immune responses
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- Pimecrolimus
- Tacrolimus
- (3R)-4-(p-toluenesulfonyl)-1,4-thiazane-3-carboxylicacid-L-phenylalanine ethyl ester
- {3-[3-(3,4-Dimethoxy-Phenyl)-1-(1-{1-[2-(3,4,5-Trimethoxy-Phenyl)-Butyryl]-Piperidin-2yl}-Vinyloxy)-Propyl]-Phenoxy}-Acetic Acid
- Gpi-1046
- Methyl Methylsulfinylmethyl Sulfide
- FKB-001
- Heptyl glucoside
- L-709,587
- (3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine
- 4-hydroxybutan-2-one
- GPI-1485
- Myristic acid
- (21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE
- Dorsomorphin
|
|
| Novel |
GATA6
|
GATA binding protein 6 |
- Surfactant metabolism
- Cardiogenesis
- Formation of definitive endoderm
- Formation of definitive endoderm
- Factors involved in megakaryocyte development and platelet production
- Developmental Lineage of Multipotent Pancreatic Progenitor Cells
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|
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| Novel |
PECAM1
|
platelet and endothelial cell adhesion molecule 1 |
- Platelet degranulation
- Cell surface interactions at the vascular wall
- PECAM1 interactions
- Integrin cell surface interactions
- Platelet sensitization by LDL
- Neutrophil degranulation
- High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
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|
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| Novel |
PRKCA
|
protein kinase C alpha |
- Calmodulin induced events
- Disinhibition of SNARE formation
- SHC1 events in ERBB2 signaling
- Signaling by SCF-KIT
- Regulation of KIT signaling
- EGFR Transactivation by Gastrin
- Inactivation, recovery and regulation of the phototransduction cascade
- Syndecan interactions
- Acetylcholine regulates insulin secretion
- Ca2+ pathway
- Trafficking of GluR2-containing AMPA receptors
- G alpha (z) signalling events
- Depolymerization of the Nuclear Lamina
- HuR (ELAVL1) binds and stabilizes mRNA
- WNT5A-dependent internalization of FZD4
- VEGFR2 mediated cell proliferation
- RHO GTPases Activate NADPH Oxidases
- Response to elevated platelet cytosolic Ca2+
- RET signaling
- ROBO receptors bind AKAP5
- ROBO receptors bind AKAP5
|
- Phosphatidyl serine
- Vitamin E
- Tamoxifen
- Staurosporine
- Dequalinium
- Ingenol mebutate
- Aprinocarsen
- Midostaurin
- Perifosine
- Ellagic acid
- Benzoyl peroxide
- Bryostatin 1
- alpha-Tocopherol succinate
- D-alpha-Tocopherol acetate
|
|
| Novel |
SMURF2
|
SMAD specific E3 ubiquitin protein ligase 2 |
- Signaling by BMP
- Downregulation of TGF-beta receptor signaling
- Downregulation of TGF-beta receptor signaling
- Downregulation of SMAD2/3:SMAD4 transcriptional activity
- Downregulation of SMAD2/3:SMAD4 transcriptional activity
- Asymmetric localization of PCP proteins
- Degradation of AXIN
- Hedgehog 'on' state
- Hedgehog 'on' state
- Ub-specific processing proteases
- Regulation of RUNX3 expression and activity
- Antigen processing: Ubiquitination & Proteasome degradation
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NMRAL1
|
NmrA like redox sensor 1 |
|
- 2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID
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|
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OIP5
|
Opa interacting protein 5 |
- Deposition of new CENPA-containing nucleosomes at the centromere
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RFX2
|
regulatory factor X2 |
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RPUSD1
|
RNA pseudouridine synthase domain containing 1 |
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SLC37A3
|
solute carrier family 37 member 3 |
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THRA
|
thyroid hormone receptor alpha |
- Nuclear Receptor transcription pathway
|
- Liothyronine
- Levothyroxine
- Dextrothyroxine
- Amiodarone
- Liotrix
- KB-141
- Dronedarone
- Eprotirome
- NRP409
- Thyroid, porcine
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TRMT6
|
tRNA methyltransferase 6 non-catalytic subunit |
- tRNA modification in the nucleus and cytosol
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TWF2
|
twinfilin actin binding protein 2 |
- Sensory processing of sound by inner hair cells of the cochlea
- Sensory processing of sound by outer hair cells of the cochlea
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