| Novel |
ANXA10
|
annexin A10 |
|
|
|
| Novel |
DECR1
|
2,4-dienoyl-CoA reductase 1 |
- mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
|
- Nicotinamide adenine dinucleotide phosphate
- 6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL
|
|
| Novel |
ETFDH
|
electron transfer flavoprotein dehydrogenase |
- Respiratory electron transport
|
- Metformin
- 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
|
- Glutaric acidemia; Glutaric acidemia, type I (GA1); Glutaric acidemia, type II (GA2); Multiple acyl coenzyme A dehydrogenase deficiency
|
| Novel |
FZD3
|
frizzled class receptor 3 |
- Class B/2 (Secretin family receptors)
- Ca2+ pathway
- Ca2+ pathway
- PCP/CE pathway
- PCP/CE pathway
- Asymmetric localization of PCP proteins
- Asymmetric localization of PCP proteins
|
|
|
| Novel |
GPRC5C
|
G protein-coupled receptor class C group 5 member C |
|
|
|
| Novel |
GRIA2
|
glutamate ionotropic receptor AMPA type subunit 2 |
- Activation of AMPA receptors
- Trafficking of GluR2-containing AMPA receptors
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- MECP2 regulates neuronal receptors and channels
- Long-term potentiation
|
- Glutamic acid
- Butabarbital
- Butalbital
- Talbutal
- Pentobarbital
- Secobarbital
- Metharbital
- Thiopental
- Primidone
- Methylphenobarbital
- Ethanol
- Phenobarbital
- Quinidine barbiturate
- Amobarbital
- Aprobarbital
- Butobarbital
- Heptabarbital
- Hexobarbital
- Barbital
- Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione
- (S)-DES-ME-AMPA
- (S)-AMPA
- 2-Amino-3-(5-Tert-Butyl-3-(Phosphonomethoxy)-4-Isoxazolyl)Propionic Acid
- Iodo-Willardiine
- Fluoro-Willardiine
- Quisqualic acid
- (S)-2-Amino-3-(1,3,5,7-Pentahydro-2,4-Dioxo-Cyclopenta[E]Pyrimidin-1-Yl) Proionic Acid
- (2S)-2-Ammonio-3-[5-(2-methyl-2-propanyl)-3-oxido-1,2-oxazol-4-yl]propanoate
- FG-9041
- Bromo-Willardiine
- Willardiine
- 2-Amino-3-(3-Hydroxy-7,8-Dihydro-6h-Cyclohepta[D]-4-Isoxazolyl)Propionic Acid
- Aniracetam
- THIO-ATPA
- Talampanel
- CX-717
- N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dimethanesulfonamide
- 2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE
- (3S)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide
- (3R)-3-cyclopentyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide
- (3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide
- Fluciclovine (18F)
|
|
| Novel |
HPF1
|
histone PARylation factor 1 |
|
|
|
| Novel |
MED23
|
mediator complex subunit 23 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- RSV-host interactions
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
|
|
|
| Novel |
NEK1
|
NIMA related kinase 1 |
- Regulation of pyruvate metabolism
|
|
- Short rib-polydactyly syndrome
|
| Novel |
PDGFB
|
platelet derived growth factor subunit B |
- Platelet degranulation
- PIP3 activates AKT signaling
- Downstream signal transduction
- Signaling by PDGF
- Constitutive Signaling by Aberrant PI3K in Cancer
- Non-integrin membrane-ECM interactions
- RAF/MAP kinase cascade
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
|
|
- Glioma
- Malignant pleural mesothelioma
|
| Novel |
VPS18
|
VPS18 core subunit of CORVET and HOPS complexes |
- SARS-CoV-2 modulates autophagy
|
|
|
|
CFTR
|
CF transmembrane conductance regulator |
- ABC-family proteins mediated transport
- RHO GTPases regulate CFTR trafficking
- Defective CFTR causes cystic fibrosis
- Ub-specific processing proteases
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- RHOQ GTPase cycle
- Chaperone Mediated Autophagy
- Late endosomal microautophagy
- Aggrephagy
- Aggrephagy
- Developmental Lineage of Pancreatic Ductal Cells
|
- ATP
- Bumetanide
- Glyburide
- Ibuprofen
- Genistein
- Colforsin
- Phosphoaminophosphonic Acid-Adenylate Ester
- Dexfosfoserine
- Crofelemer
- Lonidamine
- Ivacaftor
- Dexibuprofen
- Lumacaftor
- Tezacaftor
- Elexacaftor
|
- Hereditary pancreatitis; Hereditary chronic pancreatitis
- Cystic fibrosis (CF)
- Congenital bilateral absence of vas deferens
|
|
DNAJC5
|
DnaJ heat shock protein family (Hsp40) member C5 |
- Neutrophil degranulation
- GABA synthesis, release, reuptake and degradation
- Sensory processing of sound by inner hair cells of the cochlea
|
|
|
|
GOPC
|
golgi associated PDZ and coiled-coil motif containing |
- RHO GTPases regulate CFTR trafficking
- RHOQ GTPase cycle
|
|
|
|
HSPB1
|
heat shock protein family B (small) member 1 |
- VEGFA-VEGFR2 Pathway
- AUF1 (hnRNP D0) binds and destabilizes mRNA
- MAPK6/MAPK4 signaling
- Extra-nuclear estrogen signaling
|
- Apatorsen
- Artenimol
- Phenethyl Isothiocyanate
|
- Distal hereditary motor neuropathies (dHMN)
|
|
NHERF1
|
NHERF family PDZ scaffold protein 1 |
|
|
- Nephrolithiasis/osteoporosis, hypophosphatemic
|
|
PDZK1
|
PDZ domain containing 1 |
|
|
|