Search Results : Cancer

1954 interactions found:

Sort by: Relevance Number of Pathways Number of Drugs Number of Diseases
Novel Symbols Name 1 Name 2
Pathways 1
Pathways 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Novel
Symbols
TARS3 and LRRC28
Name 1
threonyl-tRNA synthetase 3
Name2
leucine rich repeat containing 28
Pathway 1
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Novel
Symbols
TRAF7 and HAGHL
Name 1
TNF receptor associated factor 7
Name2
hydroxyacylglutathione hydrolase like
Pathway 1
  • Antigen processing: Ubiquitination & Proteasome degradation
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Novel
Symbols
ADH1C and PKD2
Name 1
alcohol dehydrogenase 1C (class I), gamma polypeptide
Name2
polycystin 2, transient receptor potential cation channel
Pathway 1
  • RA biosynthesis pathway
  • Ethanol oxidation
Pathway 2
  • VxPx cargo-targeting to cilium
  • VxPx cargo-targeting to cilium
Drugs 1
  • NADH
  • Fomepizole
  • 2,3,4,5,6-Pentafluorobenzyl Alcohol
  • N-1-methylheptylformamide
  • 2-Ethoxyethanol
  • Cholic Acid
  • 4-Iodopyrazole
  • Pyrazole
  • Para-Bromobenzyl Alcohol
  • 3-Butylthiolane 1-Oxide
  • 5-beta-D-ribofuranosylnicotinamide adenine dinucleotide
  • (R)-N-(1-Methyl-Hexyl)-Formamide
  • Trifluoroethanol
  • Cyclohexylformamide
  • Cpad
  • N-Formylpiperidine
  • 2,3-Difluorobenzyl Alcohol
  • 2,4-Difluorobenzyl Alcohol 2,4-Difluoro-1-(Hydroxymethyl)Benzene
Drugs 2
Diseases 1
Diseases 2
  • Polycystic kidney disease
Novel
Novel
Symbols
CNNM2 and AS3MT
Name 1
cyclin and CBS domain divalent metal cation transport mediator 2
Name2
arsenite methyltransferase
Pathway 1
Pathway 2
  • Methylation
Drugs 1
Drugs 2
  • Ademetionine
Diseases 1
Diseases 2
Novel
Novel
Symbols
FAR2 and OVCH1
Name 1
fatty acyl-CoA reductase 2
Name2
ovochymase 1
Pathway 1
  • Wax biosynthesis
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Novel
Symbols
NOL10 and CIMIP5
Name 1
nucleolar protein 10
Name2
ciliary microtubule inner protein 5
Pathway 1
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Novel
Symbols
NOL10 and CYS1
Name 1
nucleolar protein 10
Name2
cystin 1
Pathway 1
Pathway 2
  • Trafficking of myristoylated proteins to the cilium
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Novel
Symbols
GPER1 and PUM3
Name 1
G protein-coupled estrogen receptor 1
Name2
pumilio RNA binding family member 3
Pathway 1
  • Peptide ligand-binding receptors
  • G alpha (i) signalling events
  • GPER1 signaling
Pathway 2
Drugs 1
  • Estradiol
  • Genistein
  • MK-0354
  • Estradiol acetate
  • Estradiol benzoate
  • Estradiol cypionate
  • Estradiol dienanthate
  • Estradiol valerate
Drugs 2
Diseases 1
Diseases 2
Novel
Novel
Symbols
B9D2 and CEACAM21
Name 1
B9 domain containing 2
Name2
CEA cell adhesion molecule 21
Pathway 1
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • Anchoring of the basal body to the plasma membrane
  • RHO GTPases Activate Formins
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Novel
Symbols
KCNC4 and TNF
Name 1
potassium voltage-gated channel subfamily C member 4
Name2
tumor necrosis factor
Pathway 1
  • Voltage gated Potassium channels
Pathway 2
  • Transcriptional regulation of white adipocyte differentiation
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • TNFR1-mediated ceramide production
  • TNFR2 non-canonical NF-kB pathway
  • Interleukin-10 signaling
  • Interleukin-4 and Interleukin-13 signaling
  • TNF signaling
  • Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells)
Drugs 1
  • Enflurane
  • Promethazine
  • Miconazole
  • Dexfosfoserine
Drugs 2
  • Etanercept
  • Adalimumab
  • Infliximab
  • Chloroquine
  • Epinephrine
  • Pseudoephedrine
  • Clenbuterol
  • Pranlukast
  • Amrinone
  • Trichostatin A
  • Afelimomab
  • YSIL6
  • SD118
  • PN0621
  • OMS-103HP
  • Talmapimod
  • VX-702
  • Atiprimod
  • CRx-139
  • CYT007-TNFQb
  • Andrographolide
  • Ethyl pyruvate
  • AME-527
  • PR-104
  • Plinabulin
  • Dexanabinol
  • Onercept
  • Golimumab
  • Certolizumab pegol
  • Pomalidomide
  • Polaprezinc
  • Foreskin fibroblast (neonatal)
  • Foreskin keratinocyte (neonatal)
  • Bryostatin 1
  • Binimetinib
  • Dilmapimod
  • Glycyrrhizic acid
Diseases 1
Diseases 2
  • Graft-versus-host disease
  • Systemic lupus erythematosus
  • Allograft rejection
  • Asthma
Novel
Novel
Symbols
CYP3A7 and SGCE
Name 1
cytochrome P450 family 3 subfamily A member 7
Name2
sarcoglycan epsilon
Pathway 1
  • Xenobiotics
Pathway 2
  • Formation of the dystrophin-glycoprotein complex (DGC)
  • Formation of the dystrophin-glycoprotein complex (DGC)
Drugs 1
  • Cannabidiol
  • Diacerein
  • Nabiximols
Drugs 2
Diseases 1
Diseases 2
  • Primary torsion dystonia (PTD)
Novel
Novel
Symbols
PHACTR2 and G3BP2
Name 1
phosphatase and actin regulator 2
Name2
G3BP stress granule assembly factor 2
Pathway 1
  • Platelet degranulation
Pathway 2
  • SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Novel
Symbols
CHST6 and NUP214
Name 1
carbohydrate sulfotransferase 6
Name2
nucleoporin 214
Pathway 1
  • Keratan sulfate biosynthesis
  • Defective CHST6 causes MCDC1
Pathway 2
  • ISG15 antiviral mechanism
  • Transport of the SLBP independent Mature mRNA
  • Transport of the SLBP Dependant Mature mRNA
  • Transport of Mature mRNA Derived from an Intronless Transcript
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • Rev-mediated nuclear export of HIV RNA
  • Transport of Ribonucleoproteins into the Host Nucleus
  • NS1 Mediated Effects on Host Pathways
  • Viral Messenger RNA Synthesis
  • NEP/NS2 Interacts with the Cellular Export Machinery
  • Regulation of Glucokinase by Glucokinase Regulatory Protein
  • Nuclear import of Rev protein
  • Vpr-mediated nuclear import of PICs
  • IPs transport between nucleus and cytosol
  • IP3 and IP4 transport between cytosol and nucleus
  • IP6 and IP7 transport between cytosol and nucleus
  • snRNP Assembly
  • SUMOylation of DNA damage response and repair proteins
  • SUMOylation of ubiquitinylation proteins
  • Nuclear Pore Complex (NPC) Disassembly
  • Regulation of HSF1-mediated heat shock response
  • SUMOylation of SUMOylation proteins
  • HuR (ELAVL1) binds and stabilizes mRNA
  • SUMOylation of chromatin organization proteins
  • SUMOylation of RNA binding proteins
  • SUMOylation of DNA replication proteins
  • SUMOylation of DNA replication proteins
  • Transcriptional regulation by small RNAs
  • Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
  • tRNA processing in the nucleus
  • HCMV Early Events
  • HCMV Late Events
  • SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs 1
Drugs 2
Diseases 1
  • Macular corneal dystrophy (MCD); Corneal dystrophy Groenouw type II; Fehr corneal dystrophy
Diseases 2
Novel
Novel
Symbols
FSTL4 and JADE2
Name 1
follistatin like 4
Name2
jade family PHD finger 2
Pathway 1
Pathway 2
  • HATs acetylate histones
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Novel
Symbols
NME8 and SUGCT
Name 1
NME/NM23 family member 8
Name2
succinyl-CoA:glutarate-CoA transferase
Pathway 1
Pathway 2
Drugs 1
Drugs 2
Diseases 1
  • Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome
Diseases 2
Novel
Novel
Symbols
SHISA3 and BEND4
Name 1
shisa family member 3
Name2
BEN domain containing 4
Pathway 1
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Novel
Symbols
SLC24A3 and FASTKD5
Name 1
solute carrier family 24 member 3
Name2
FAST kinase domains 5
Pathway 1
  • Sodium/Calcium exchangers
Pathway 2
  • FASTK family proteins regulate processing and stability of mitochondrial RNAs
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Novel
Symbols
MACROD2 and ISM1
Name 1
mono-ADP ribosylhydrolase 2
Name2
isthmin 1
Pathway 1
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Novel
Symbols
TTC9 and SMOC1
Name 1
tetratricopeptide repeat domain 9
Name2
SPARC related modular calcium binding 1
Pathway 1
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Novel
Symbols
KCNG4 and DNAAF1
Name 1
potassium voltage-gated channel modifier subfamily G member 4
Name2
dynein axonemal assembly factor 1
Pathway 1
  • Voltage gated Potassium channels
Pathway 2
Drugs 1
  • Enflurane
  • Promethazine
  • Miconazole
Drugs 2
Diseases 1
Diseases 2
Novel
Symbols
TARS3 and LRRC28
Name 1
threonyl-tRNA synthetase 3
Name2
leucine rich repeat containing 28
Pathway 1
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Symbols
TRAF7 and HAGHL
Name 1
TNF receptor associated factor 7
Name2
hydroxyacylglutathione hydrolase like
Pathway 1
  • Antigen processing: Ubiquitination & Proteasome degradation
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Symbols
ADH1C and PKD2
Name 1
alcohol dehydrogenase 1C (class I), gamma polypeptide
Name2
polycystin 2, transient receptor potential cation channel
Pathway 1
  • RA biosynthesis pathway
  • Ethanol oxidation
Pathway 2
  • VxPx cargo-targeting to cilium
  • VxPx cargo-targeting to cilium
Drugs 1
  • NADH
  • Fomepizole
  • 2,3,4,5,6-Pentafluorobenzyl Alcohol
  • N-1-methylheptylformamide
  • 2-Ethoxyethanol
  • Cholic Acid
  • 4-Iodopyrazole
  • Pyrazole
  • Para-Bromobenzyl Alcohol
  • 3-Butylthiolane 1-Oxide
  • 5-beta-D-ribofuranosylnicotinamide adenine dinucleotide
  • (R)-N-(1-Methyl-Hexyl)-Formamide
  • Trifluoroethanol
  • Cyclohexylformamide
  • Cpad
  • N-Formylpiperidine
  • 2,3-Difluorobenzyl Alcohol
  • 2,4-Difluorobenzyl Alcohol 2,4-Difluoro-1-(Hydroxymethyl)Benzene
Drugs 2
Diseases 1
Diseases 2
  • Polycystic kidney disease
Novel
Symbols
CNNM2 and AS3MT
Name 1
cyclin and CBS domain divalent metal cation transport mediator 2
Name2
arsenite methyltransferase
Pathway 1
Pathway 2
  • Methylation
Drugs 1
Drugs 2
  • Ademetionine
Diseases 1
Diseases 2
Novel
Symbols
FAR2 and OVCH1
Name 1
fatty acyl-CoA reductase 2
Name2
ovochymase 1
Pathway 1
  • Wax biosynthesis
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Symbols
NOL10 and CIMIP5
Name 1
nucleolar protein 10
Name2
ciliary microtubule inner protein 5
Pathway 1
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Symbols
NOL10 and CYS1
Name 1
nucleolar protein 10
Name2
cystin 1
Pathway 1
Pathway 2
  • Trafficking of myristoylated proteins to the cilium
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Symbols
GPER1 and PUM3
Name 1
G protein-coupled estrogen receptor 1
Name2
pumilio RNA binding family member 3
Pathway 1
  • Peptide ligand-binding receptors
  • G alpha (i) signalling events
  • GPER1 signaling
Pathway 2
Drugs 1
  • Estradiol
  • Genistein
  • MK-0354
  • Estradiol acetate
  • Estradiol benzoate
  • Estradiol cypionate
  • Estradiol dienanthate
  • Estradiol valerate
Drugs 2
Diseases 1
Diseases 2
Novel
Symbols
B9D2 and CEACAM21
Name 1
B9 domain containing 2
Name2
CEA cell adhesion molecule 21
Pathway 1
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • Anchoring of the basal body to the plasma membrane
  • RHO GTPases Activate Formins
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Symbols
KCNC4 and TNF
Name 1
potassium voltage-gated channel subfamily C member 4
Name2
tumor necrosis factor
Pathway 1
  • Voltage gated Potassium channels
Pathway 2
  • Transcriptional regulation of white adipocyte differentiation
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • TNFR1-mediated ceramide production
  • TNFR2 non-canonical NF-kB pathway
  • Interleukin-10 signaling
  • Interleukin-4 and Interleukin-13 signaling
  • TNF signaling
  • Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells)
Drugs 1
  • Enflurane
  • Promethazine
  • Miconazole
  • Dexfosfoserine
Drugs 2
  • Etanercept
  • Adalimumab
  • Infliximab
  • Chloroquine
  • Epinephrine
  • Pseudoephedrine
  • Clenbuterol
  • Pranlukast
  • Amrinone
  • Trichostatin A
  • Afelimomab
  • YSIL6
  • SD118
  • PN0621
  • OMS-103HP
  • Talmapimod
  • VX-702
  • Atiprimod
  • CRx-139
  • CYT007-TNFQb
  • Andrographolide
  • Ethyl pyruvate
  • AME-527
  • PR-104
  • Plinabulin
  • Dexanabinol
  • Onercept
  • Golimumab
  • Certolizumab pegol
  • Pomalidomide
  • Polaprezinc
  • Foreskin fibroblast (neonatal)
  • Foreskin keratinocyte (neonatal)
  • Bryostatin 1
  • Binimetinib
  • Dilmapimod
  • Glycyrrhizic acid
Diseases 1
Diseases 2
  • Graft-versus-host disease
  • Systemic lupus erythematosus
  • Allograft rejection
  • Asthma
Novel
Symbols
CYP3A7 and SGCE
Name 1
cytochrome P450 family 3 subfamily A member 7
Name2
sarcoglycan epsilon
Pathway 1
  • Xenobiotics
Pathway 2
  • Formation of the dystrophin-glycoprotein complex (DGC)
  • Formation of the dystrophin-glycoprotein complex (DGC)
Drugs 1
  • Cannabidiol
  • Diacerein
  • Nabiximols
Drugs 2
Diseases 1
Diseases 2
  • Primary torsion dystonia (PTD)
Novel
Symbols
PHACTR2 and G3BP2
Name 1
phosphatase and actin regulator 2
Name2
G3BP stress granule assembly factor 2
Pathway 1
  • Platelet degranulation
Pathway 2
  • SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Symbols
CHST6 and NUP214
Name 1
carbohydrate sulfotransferase 6
Name2
nucleoporin 214
Pathway 1
  • Keratan sulfate biosynthesis
  • Defective CHST6 causes MCDC1
Pathway 2
  • ISG15 antiviral mechanism
  • Transport of the SLBP independent Mature mRNA
  • Transport of the SLBP Dependant Mature mRNA
  • Transport of Mature mRNA Derived from an Intronless Transcript
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • Rev-mediated nuclear export of HIV RNA
  • Transport of Ribonucleoproteins into the Host Nucleus
  • NS1 Mediated Effects on Host Pathways
  • Viral Messenger RNA Synthesis
  • NEP/NS2 Interacts with the Cellular Export Machinery
  • Regulation of Glucokinase by Glucokinase Regulatory Protein
  • Nuclear import of Rev protein
  • Vpr-mediated nuclear import of PICs
  • IPs transport between nucleus and cytosol
  • IP3 and IP4 transport between cytosol and nucleus
  • IP6 and IP7 transport between cytosol and nucleus
  • snRNP Assembly
  • SUMOylation of DNA damage response and repair proteins
  • SUMOylation of ubiquitinylation proteins
  • Nuclear Pore Complex (NPC) Disassembly
  • Regulation of HSF1-mediated heat shock response
  • SUMOylation of SUMOylation proteins
  • HuR (ELAVL1) binds and stabilizes mRNA
  • SUMOylation of chromatin organization proteins
  • SUMOylation of RNA binding proteins
  • SUMOylation of DNA replication proteins
  • SUMOylation of DNA replication proteins
  • Transcriptional regulation by small RNAs
  • Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
  • tRNA processing in the nucleus
  • HCMV Early Events
  • HCMV Late Events
  • SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs 1
Drugs 2
Diseases 1
  • Macular corneal dystrophy (MCD); Corneal dystrophy Groenouw type II; Fehr corneal dystrophy
Diseases 2
Novel
Symbols
FSTL4 and JADE2
Name 1
follistatin like 4
Name2
jade family PHD finger 2
Pathway 1
Pathway 2
  • HATs acetylate histones
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Symbols
NME8 and SUGCT
Name 1
NME/NM23 family member 8
Name2
succinyl-CoA:glutarate-CoA transferase
Pathway 1
Pathway 2
Drugs 1
Drugs 2
Diseases 1
  • Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome
Diseases 2
Novel
Symbols
SHISA3 and BEND4
Name 1
shisa family member 3
Name2
BEN domain containing 4
Pathway 1
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Symbols
SLC24A3 and FASTKD5
Name 1
solute carrier family 24 member 3
Name2
FAST kinase domains 5
Pathway 1
  • Sodium/Calcium exchangers
Pathway 2
  • FASTK family proteins regulate processing and stability of mitochondrial RNAs
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Symbols
MACROD2 and ISM1
Name 1
mono-ADP ribosylhydrolase 2
Name2
isthmin 1
Pathway 1
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Symbols
TTC9 and SMOC1
Name 1
tetratricopeptide repeat domain 9
Name2
SPARC related modular calcium binding 1
Pathway 1
Pathway 2
Drugs 1
Drugs 2
Diseases 1
Diseases 2
Novel
Symbols
KCNG4 and DNAAF1
Name 1
potassium voltage-gated channel modifier subfamily G member 4
Name2
dynein axonemal assembly factor 1
Pathway 1
  • Voltage gated Potassium channels
Pathway 2
Drugs 1
  • Enflurane
  • Promethazine
  • Miconazole
Drugs 2
Diseases 1
Diseases 2

Page 5 out of 98 pages

© Madhavi K. Ganapathiraju 2012-2025