CYP3A7 and SGCE

		CYP3A7	SGCE
Description		cytochrome P450 family 3 subfamily A member 7	sarcoglycan epsilon
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Membrane Dendrite Dendrite Membrane Sarcolemma Cell Projection
	Molecular Function	Monooxygenase Activity Iron Ion Binding Steroid Hydroxylase Activity Retinoic Acid 4-hydroxylase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Oxygen Binding Heme Binding Metal Ion Binding Testosterone 6-beta-hydroxylase Activity All-trans Retinoic Acid 18-hydroxylase Activity Estrogen 16-alpha-hydroxylase Activity Estrogen 2-hydroxylase Activity
	Biological Process	Lipid Hydroxylation Lipid Metabolic Process Steroid Biosynthetic Process Xenobiotic Metabolic Process Steroid Metabolic Process Estrogen Metabolic Process Retinol Metabolic Process Retinoic Acid Metabolic Process Oxidative Demethylation	Cell-matrix Adhesion Muscle Organ Development
Pathways		Xenobiotics	Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs		Cannabidiol Diacerein Nabiximols
Diseases			Primary torsion dystonia (PTD)
GWAS		Endometrial cancer ( 30093612) Estradiol levels ( 34255042) Serum metabolite levels ( 23093944 33031748) Sex hormone levels ( 26014426) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes			4 interacting genes: ARIH2 CWC15 KEAP1 PPP1CC
Entrez ID		1551	8910
HPRD ID		05630	04999
Ensembl ID		ENSG00000160870	ENSG00000127990
Uniprot IDs		P24462	A0A0S2Z4P5 A0A2R8Y448 A0A2R8Y5J3 A0A2R8YGQ3 B4DP78 C9JR67 E9PEH6 O43556
PDB IDs		7MK8
Enriched GO Terms of Interacting Partners?		Sarcoglycan Complex Dystrophin-associated Glycoprotein Complex Dendrite Membrane Muscle Organ Development Sarcolemma Muscle Structure Development Cell-substrate Adhesion Cell-matrix Adhesion
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