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MIRLET7F2 |
microRNA let-7f-2 |
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MIRLET7G |
microRNA let-7g |
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MIRLET7I |
microRNA let-7i |
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NFKB1 |
nuclear factor kappa B subunit 1 |
- Activation of NF-kappaB in B cells
- RIP-mediated NFkB activation via ZBP1
- Regulated proteolysis of p75NTR
- Downstream TCR signaling
- NF-kB is activated and signals survival
- Senescence-Associated Secretory Phenotype (SASP)
- FCERI mediated NF-kB activation
- DEx/H-box helicases activate type I IFN and inflammatory cytokines production
- PKMTs methylate histone lysines
- Transcriptional regulation of white adipocyte differentiation
- TAK1-dependent IKK and NF-kappa-B activation
- Interleukin-1 processing
- IkBA variant leads to EDA-ID
- CLEC7A (Dectin-1) signaling
- CD209 (DC-SIGN) signaling
- CLEC7A/inflammasome pathway
- MAP3K8 (TPL2)-dependent MAPK1/3 activation
- Neutrophil degranulation
- The NLRP3 inflammasome
- Transcriptional Regulation by VENTX
- Interleukin-1 signaling
- TRAF6 mediated NF-kB activation
- HCMV Early Events
- Purinergic signaling in leishmaniasis infection
- SARS-CoV-1 activates/modulates innate immune responses
- Regulation of NFE2L2 gene expression
- Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
- Regulation of PD-L1(CD274) transcription
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- Sulfasalazine
- Donepezil
- Pseudoephedrine
- Pranlukast
- Pranlukast
- HE3286
- P54
- NOX-700
- SGN-30
- Custirsen
- NF-kappaB Decoy
- Andrographolide
- Triflusal
- Terpinen-4-ol
- Glycyrrhizic acid
- Fish oil
- SC-236
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NFKBIA |
NFKB inhibitor alpha |
- Activation of NF-kappaB in B cells
- RIP-mediated NFkB activation via ZBP1
- Downstream TCR signaling
- NF-kB is activated and signals survival
- FCERI mediated NF-kB activation
- TAK1-dependent IKK and NF-kappa-B activation
- SUMOylation of immune response proteins
- IkBA variant leads to EDA-ID
- CLEC7A (Dectin-1) signaling
- Ub-specific processing proteases
- Interleukin-1 signaling
- TRAF6 mediated NF-kB activation
- SARS-CoV-1 activates/modulates innate immune responses
- Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
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- Acetylsalicylic acid
- Bardoxolone methyl
- Astaxanthin
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- Hodgkin lymphoma
- Ectodermal dysplasia associated immunodeficiency (EDA-ID), including the following two diseases: NF-kappa-B essential modulator (NEMO) defect; Inhibitor of kappa-B (I-kappa-B) defect
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OGT |
O-linked N-acetylglucosamine (GlcNAc) transferase |
- HATs acetylate histones
- RIPK1-mediated regulated necrosis
- Regulation of necroptotic cell death
- UCH proteinases
- Formation of WDR5-containing histone-modifying complexes
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PDE4B |
phosphodiesterase 4B |
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- Adenosine phosphate
- Caffeine
- Caffeine
- Theophylline
- Dyphylline
- Enprofylline
- Iloprost
- Papaverine
- Theobromine
- Amrinone
- Daxalipram
- Roflumilast
- Piclamilast
- Rolipram
- Rolipram
- 3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester
- Filaminast
- 8-Bromo-Adenosine-5'-Monophosphate
- (S)-Rolipram
- 1-(2-Chlorophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester
- Cilomilast
- (R)-Rolipram
- S,S-(2-Hydroxyethyl)Thiocysteine
- Crisaborole
- Ibudilast
- 1-ethyl-N-(phenylmethyl)-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
- 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid
- Trapidil
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PIN1 |
peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
- ISG15 antiviral mechanism
- RHO GTPases Activate NADPH Oxidases
- Regulation of TP53 Activity through Phosphorylation
- PI5P Regulates TP53 Acetylation
- Negative regulators of DDX58/IFIH1 signaling
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- Beta-(2-Naphthyl)-Alanine
- 3,6,9,12,15,18-HEXAOXAICOSANE
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PRMT5 |
protein arginine methyltransferase 5 |
- snRNP Assembly
- RMTs methylate histone arginines
- Regulation of TP53 Activity through Methylation
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RIOK1 |
RIO kinase 1 |
- Major pathway of rRNA processing in the nucleolus and cytosol
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TRIM25 |
tripartite motif containing 25 |
- ISG15 antiviral mechanism
- DDX58/IFIH1-mediated induction of interferon-alpha/beta
- Termination of translesion DNA synthesis
- Ovarian tumor domain proteases
- Interferon gamma signaling
- TRAF3-dependent IRF activation pathway
- TRAF6 mediated IRF7 activation
- TRAF6 mediated NF-kB activation
- TRAF6 mediated NF-kB activation
- NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
- Negative regulators of DDX58/IFIH1 signaling
- Negative regulators of DDX58/IFIH1 signaling
- SARS-CoV-1 activates/modulates innate immune responses
- SARS-CoV-2 activates/modulates innate and adaptive immune responses
- Evasion by RSV of host interferon responses
- RSV-host interactions
- PKR-mediated signaling
- Modulation of host responses by IFN-stimulated genes
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USP10 |
ubiquitin specific peptidase 10 |
- Termination of translesion DNA synthesis
- Ub-specific processing proteases
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ZNF618 |
zinc finger protein 618 |
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