G3BP2

Gene Name		GTPase activating protein (SH3 domain) binding protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm
	Molecular Function	Nucleotide Binding Receptor Signaling Complex Scaffold Activity Poly(A) RNA Binding
	Biological Process	Cytoplasmic Sequestering Of NF-kappaB Ras Protein Signal Transduction MRNA Transport
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: MDM2 NFKB1 NFKBIA PIN1 USP10
Entrez ID		9908
HPRD ID		06570
Ensembl ID		ENSG00000138757
Uniprot IDs		Q9UN86
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Type I Interferon Production Regulation Of Cellular Protein Metabolic Process Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Metabolic Process Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Fc Receptor Signaling Pathway Regulation Of Cholesterol Transport Cellular Response To Alkaloid Regulation Of Macrophage Derived Foam Cell Differentiation Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response Toll-like Receptor 5 Signaling Pathway Defense Response Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Intracellular Signal Transduction Cellular Response To Lipid Regulation Of Lipid Storage Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Response To Stress TRIF-dependent Toll-like Receptor Signaling Pathway Immune Response-regulating Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Response To Peptide MyD88-dependent Toll-like Receptor Signaling Pathway DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Type I Interferon Production Toll-like Receptor 4 Signaling Pathway Regulation Of Cytokine Production Signal Transduction In Response To DNA Damage Cellular Response To Growth Factor Stimulus Regulation Of Lipid Transport Response To Growth Factor Intracellular Signal Transduction Cellular Response To Organic Substance Toll-like Receptor Signaling Pathway Signal Transduction By P53 Class Mediator Cellular Response To UV-C Cellular Response To Vitamin B1 Negative Regulation Of Interleukin-12 Biosynthetic Process T Cell Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction
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