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MSC |
musculin |
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MYF6 |
myogenic factor 6 |
- Myogenesis
- Myogenesis
- TGFBR3 expression
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- Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
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MYO15B |
myosin XVB |
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NAGK |
N-acetylglucosamine kinase |
- Synthesis of UDP-N-acetyl-glucosamine
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NEK6 |
NIMA related kinase 6 |
- Activation of NIMA Kinases NEK9, NEK6, NEK7
- Nuclear Pore Complex (NPC) Disassembly
- EML4 and NUDC in mitotic spindle formation
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NEUROD1 |
neuronal differentiation 1 |
- Regulation of gene expression in beta cells
- Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells
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- Maturity onset diabetes of the young (MODY)
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NEUROG1 |
neurogenin 1 |
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NGLY1 |
N-glycanase 1 |
- N-glycan trimming in the ER and Calnexin/Calreticulin cycle
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NHLH2 |
nescient helix-loop-helix 2 |
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OLIG3 |
oligodendrocyte transcription factor 3 |
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OSGIN1 |
oxidative stress induced growth inhibitor 1 |
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PIN1 |
peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
- ISG15 antiviral mechanism
- RHO GTPases Activate NADPH Oxidases
- Regulation of TP53 Activity through Phosphorylation
- PI5P Regulates TP53 Acetylation
- Negative regulators of DDX58/IFIH1 signaling
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- Beta-(2-Naphthyl)-Alanine
- 3,6,9,12,15,18-HEXAOXAICOSANE
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PRKAB2 |
protein kinase AMP-activated non-catalytic subunit beta 2 |
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- Macroautophagy
- AMPK inhibits chREBP transcriptional activation activity
- AMPK inhibits chREBP transcriptional activation activity
- Carnitine shuttle
- Activation of PPARGC1A (PGC-1alpha) by phosphorylation
- Energy dependent regulation of mTOR by LKB1-AMPK
- TP53 Regulates Metabolic Genes
- Regulation of TP53 Activity through Phosphorylation
- Lipophagy
- Activation of AMPK downstream of NMDARs
- AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
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- Adenosine phosphate
- Acetylsalicylic acid
- Fostamatinib
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PRSS23 |
serine protease 23 |
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- Post-translational protein phosphorylation
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PSMA1 |
proteasome 20S subunit alpha 1 |
- Activation of NF-kappaB in B cells
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
- ER-Phagosome pathway
- ER-Phagosome pathway
- Cross-presentation of soluble exogenous antigens (endosomes)
- Autodegradation of Cdh1 by Cdh1:APC/C
- SCF-beta-TrCP mediated degradation of Emi1
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Vpu mediated degradation of CD4
- Vif-mediated degradation of APOBEC3G
- SCF(Skp2)-mediated degradation of p27/p21
- Degradation of beta-catenin by the destruction complex
- Downstream TCR signaling
- Regulation of activated PAK-2p34 by proteasome mediated degradation
- Separation of Sister Chromatids
- FCERI mediated NF-kB activation
- Autodegradation of the E3 ubiquitin ligase COP1
- Regulation of ornithine decarboxylase (ODC)
- ABC-family proteins mediated transport
- AUF1 (hnRNP D0) binds and destabilizes mRNA
- Asymmetric localization of PCP proteins
- Degradation of AXIN
- Degradation of DVL
- Hedgehog ligand biogenesis
- Hh mutants are degraded by ERAD
- Dectin-1 mediated noncanonical NF-kB signaling
- CLEC7A (Dectin-1) signaling
- Degradation of GLI1 by the proteasome
- Degradation of GLI2 by the proteasome
- GLI3 is processed to GLI3R by the proteasome
- Hedgehog 'on' state
- Regulation of RAS by GAPs
- TNFR2 non-canonical NF-kB pathway
- NIK-->noncanonical NF-kB signaling
- Defective CFTR causes cystic fibrosis
- MAPK6/MAPK4 signaling
- UCH proteinases
- Ub-specific processing proteases
- Assembly of the pre-replicative complex
- Orc1 removal from chromatin
- CDK-mediated phosphorylation and removal of Cdc6
- G2/M Checkpoints
- Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A
- Ubiquitin-dependent degradation of Cyclin D
- The role of GTSE1 in G2/M progression after G2 checkpoint
- FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Regulation of RUNX2 expression and activity
- Regulation of RUNX2 expression and activity
- Regulation of RUNX3 expression and activity
- Regulation of PTEN stability and activity
- Neddylation
- Regulation of expression of SLITs and ROBOs
- Interleukin-1 signaling
- Negative regulation of NOTCH4 signaling
- KEAP1-NFE2L2 pathway
- GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2
- Degradation of CDH1
- Somitogenesis
- Antigen processing: Ubiquitination & Proteasome degradation
- Proteasome assembly
- Proteasome assembly
- Antigen processing: Ub, ATP-independent proteasomal degradation
- GSK3B-mediated proteasomal degradation of PD-L1(CD274)
- SPOP-mediated proteasomal degradation of PD-L1(CD274)
- AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
- Degradation of CRY and PER proteins
- Degradation of CRY and PER proteins
- Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
- Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
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- (3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE
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PTF1A |
pancreas associated transcription factor 1a |
- Regulation of gene expression in early pancreatic precursor cells
- Developmental Lineage of Pancreatic Acinar Cells
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- Permanent neonatal diabetes mellitus (PNDM)
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QARS1 |
glutaminyl-tRNA synthetase 1 |
- Selenoamino acid metabolism
- Cytosolic tRNA aminoacylation
- Mitochondrial tRNA aminoacylation
- Transcriptional and post-translational regulation of MITF-M expression and activity
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RBM8A |
RNA binding motif protein 8A |
- Transport of Mature mRNA derived from an Intron-Containing Transcript
- mRNA Splicing - Major Pathway
- mRNA 3'-end processing
- RNA Polymerase II Transcription Termination
- Regulation of expression of SLITs and ROBOs
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
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RNASEL |
ribonuclease L |
- OAS antiviral response
- Interferon alpha/beta signaling
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RUNX1T1 |
RUNX1 partner transcriptional co-repressor 1 |
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- Acute myeloid leukemia (AML)
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