GRIPAP1 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
DNAAF19	dynein axonemal assembly factor 19
DRC4	dynein regulatory complex subunit 4	Activation of SMO
DUSP26	dual specificity phosphatase 26
EHHADH	enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase	Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import	NADH
ELOA	elongin A	Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
ENKD1	enkurin domain containing 1
FAM161A	FAM161 centrosomal protein A			Retinitis pigmentosa (RP)
FAM50B	family with sequence similarity 50 member B
FAM90A1	family with sequence similarity 90 member A1
FXR1	FMR1 autosomal homolog 1	Signaling by BRAF and RAF1 fusions
GRIA1	glutamate ionotropic receptor AMPA type subunit 1	COPII-mediated vesicle transport Activation of AMPA receptors Trafficking of AMPA receptors Trafficking of GluR2-containing AMPA receptors Unblocking of NMDA receptors, glutamate binding and activation Unblocking of NMDA receptors, glutamate binding and activation Cargo concentration in the ER Synaptic adhesion-like molecules Long-term potentiation	Glutamic acid Butabarbital Lamotrigine Isoflurane Ethanol Methoxyflurane Desflurane Sevoflurane Talampanel CX-717 CX516 Perampanel Tianeptine Fluciclovine (18F)
GRIP1	glutamate receptor interacting protein 1	Trafficking of GluR2-containing AMPA receptors
GRM7	glutamate metabotropic receptor 7	G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors)	Glutamic acid
HDAC4	histone deacetylase 4	NOTCH1 Intracellular Domain Regulates Transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway SUMOylation of intracellular receptors SUMOylation of chromatin organization proteins RUNX2 regulates chondrocyte maturation RUNX3 regulates p14-ARF	Valproic acid Decitabine Zinc Vorinostat Belinostat Romidepsin Romidepsin Panobinostat Phenylbutyric acid N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide 2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL Entinostat Abexinostat Givinostat Pyroxamide Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Brachydacytly-mental retardation syndrome and Smith-Magenis syndrome
HSPB1	heat shock protein family B (small) member 1	VEGFA-VEGFR2 Pathway AUF1 (hnRNP D0) binds and destabilizes mRNA MAPK6/MAPK4 signaling Extra-nuclear estrogen signaling	Apatorsen Artenimol Phenethyl Isothiocyanate	Distal hereditary motor neuropathies (dHMN)
ING4	inhibitor of growth family member 4	HATs acetylate histones
ING5	inhibitor of growth family member 5	HATs acetylate histones Regulation of TP53 Activity through Acetylation
LNX1	ligand of numb-protein X 1	Antigen processing: Ubiquitination & Proteasome degradation
MAP3K1	mitogen-activated protein kinase kinase kinase 1	MyD88:MAL(TIRAP) cascade initiated on plasma membrane FCERI mediated MAPK activation FCERI mediated MAPK activation TRAF6 mediated NF-kB activation TRAF6 mediated NF-kB activation TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation MyD88 cascade initiated on plasma membrane	AZD-8330 Binimetinib Fostamatinib
MEOX2	mesenchyme homeobox 2

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