Search Results for: EXOSC5

86 interactions involving EXOSC5 - exosome component 5 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
EXOSC1 exosome component 1
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Nuclear RNA decay
EXOSC10 exosome component 10
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Nuclear RNA decay
EXOSC2 exosome component 2
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Nuclear RNA decay
EXOSC3 exosome component 3
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Nuclear RNA decay
EXOSC6 exosome component 6
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Nuclear RNA decay
EXOSC7 exosome component 7
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Nuclear RNA decay
EXOSC8 exosome component 8
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Nuclear RNA decay
EXOSC9 exosome component 9
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Nuclear RNA decay
FCHO1 FCH and mu domain containing endocytic adaptor 1
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
FH fumarate hydratase
  • Citric acid cycle (TCA cycle)
  • Mitochondrial protein degradation
  • Diseases of the tricarboxylic acid cycle, including: Fumarase (FH) deficiency; Succinate dehydrogenase (SDH) deficiency; Alpha-ketoglutarate dehydrogenase (AKGDH) deficiency
  • Multiple cutaneous and uterine leiomyomata
  • Renal cell carcinoma
FHL3 four and a half LIM domains 3
GOLGA2 golgin A2
  • Golgi Cisternae Pericentriolar Stack Reorganization
  • Golgi Cisternae Pericentriolar Stack Reorganization
  • COPII-mediated vesicle transport
  • COPI-mediated anterograde transport
  • Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
HOXC4 homeobox C4
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
IKZF3 IKAROS family zinc finger 3
KCTD13 potassium channel tetramerization domain containing 13
  • RND3 GTPase cycle
  • RND2 GTPase cycle
KIAA1217 KIAA1217
KRT13 keratin 13
  • Keratinization
  • Formation of the cornified envelope
  • White sponge nevus
KRT27 keratin 27
  • Keratinization
  • Formation of the cornified envelope
KRT31 keratin 31
  • Keratinization
  • Formation of the cornified envelope
KRT34 keratin 34
  • Keratinization
  • Formation of the cornified envelope

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