NUP58 and SHISA2

Data Source: HiPPIP (Novel)

		NUP58	SHISA2
Name		nucleoporin 58	shisa family member 2
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Membrane Nuclear Membrane Protein-containing Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein-containing Complex Binding	Protein Binding
	Biological Process	Nucleocytoplasmic Transport Protein Transport Regulation Of Protein Import Into Nucleus MRNA Transport	Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		19 interacting genes: ABI3 AGR2 APC COG3 COG6 HTT KRT27 KRT28 KRT33B MAPK3 MEIS2 MIS18A NUP62 PKNOX1 PKNOX2 TRAF1 TRIM54 UBQLN1 UBQLN2	2 interacting genes: ATXN1L LNX2
Entrez ID		9818	387914
HPRD ID		06355	16589
Ensembl ID		ENSG00000139496	ENSG00000180730
Uniprot IDs		A0A8Q3WKK5 A0A8Q3WKL7 Q9BVL2	Q6UWI4
PDB IDs		4JO7 4JO9 4JQ5 5IJN 5IJO 7PER 7R5J 7R5K	Not available
GO Terms Enriched among Interactors		Positive Regulation Of Protein Localization To Centrosome Regulation Of Protein Localization To Centrosome Organelle Organization Regulation Of Macroautophagy Structural Constituent Of Skin Epidermis Intermediate Filament Organization Positive Regulation Of Response To Endoplasmic Reticulum Stress Golgi Transport Complex Retrograde Transport, Vesicle Recycling Within Golgi Anatomical Structure Morphogenesis Autophagosome Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Autophagosome Assembly Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of ERAD Pathway Regulation Of Organelle Assembly Autophagosome Organization Regulation Of Organelle Organization Golgi Organization Regulation Of ERAD Pathway Positive Regulation Of Catabolic Process Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Hair Follicle Morphogenesis Identical Protein Binding Positive Regulation Of ERBB Signaling Pathway Intra-Golgi Vesicle-mediated Transport Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule Depolymerization Regulation Of Protein Catabolic Process Regulation Of Protein Stability Regulation Of Autophagy Intermediate Filament Polyubiquitin Modification-dependent Protein Binding Negative Regulation Of Microtubule Polymerization Or Depolymerization Cytoskeleton Epithelial Cell Differentiation Structural Molecule Activity Vacuole Organization Negative Regulation Of Store-operated Calcium Channel Activity Tissue Morphogenesis Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Peptidyl-tyrosine Phosphorylation Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of G Protein-coupled Receptor Internalization	None