PTGFRN and CD151

Number of citations: 0 (PubMedID 11278880)
Data Source: BioGRID (affinity chromatography technology), HPRD (in vitro, in vivo)

		PTGFRN	CD151
Name		prostaglandin F2 receptor inhibitor	CD151 molecule (Raph blood group)
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cell Surface Membrane	Basement Membrane Cytosol Plasma Membrane Focal Adhesion Cell Surface Membrane
	Molecular Function	Protein Binding	Integrin Binding Protein Binding
	Biological Process	Myoblast Fusion Involved In Skeletal Muscle Regeneration Lipid Droplet Organization	Cell Adhesion Cell Migration Positive Regulation Of Cell Migration T Cell Proliferation Wound Healing, Spreading Of Cells Positive Regulation Of Endocytosis
Pathways		None	Assembly of collagen fibrils and other multimeric structures Type I hemidesmosome assembly
Diseases		None	Nephropathy with pretibial epidermolysis bullosa and deafness
GWAS		Blood protein levels ( 30072576 ) Erectile dysfunction and prostate cancer treatment ( 20932654 ) Gout (normal type) ( 32238385 ) Low susceptibility to hepatitis C infection ( 31206233 ) T-Cell Immunoglobulin and Mucin domain 1 levels ( 32460577 ) Type 2 diabetes ( 30054458 30297969 )	Mean platelet volume ( 27863252 32888494 ) Platelet count ( 32888494 )
Interacting Genes		5 interacting genes: CD151 CD63 CD81 CD82 CD9	12 interacting genes: ARL13B BCL7A GRAMD1C ITGA3 ITGA6 ITGB1 KLRC1 MMP7 PTGFRN RNF128 TMEM139 TSPAN18
Entrez ID		5738	977
HPRD ID		03124	03763
Ensembl ID		ENSG00000134247	ENSG00000177697
Uniprot IDs		Q9P2B2	P48509 Q6ZNZ0
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Myoblast Fusion Involved In Skeletal Muscle Regeneration Integrin Binding Cellular Response To Lipoprotein Particle Stimulus Myoblast Fusion Regulation Of Cell Migration Cell-cell Fusion Cellular Response To Low-density Lipoprotein Particle Stimulus Syncytium Formation Syncytium Formation By Plasma Membrane Fusion Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Macrophage Migration Cell-cell Recognition Focal Adhesion Receptor Internalization Pigment Granule Maturation Macrophage Fusion Positive Regulation Of Adaptive Immune Memory Response CD4-positive, Alpha-beta T Cell Costimulation Cell Recognition Cell Surface Regulation Of Mononuclear Cell Migration Positive Regulation Of Endocytosis Cellular Pigment Accumulation Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Regulation Of Cell Adhesion Extracellular Exosome Receptor-mediated Endocytosis Positive Regulation Of Transport Vesicle Cell Adhesion Cellular Pigmentation Plasma Membrane Cell Migration Multivesicular Body, Internal Vesicle Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Leukocyte Migration Paranodal Junction Assembly Platelet Dense Granule Membrane MHC Class II Protein Binding Osteoclast Fusion Cell Motility Positive Regulation Of Protein Catabolic Process In The Vacuole Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of T-helper 2 Cell Cytokine Production Tetraspanin-enriched Microdomain Endosome To Melanosome Transport Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of Protein Exit From Endoplasmic Reticulum Negative Regulation Of Platelet Aggregation	Integrin Alpha6-beta1 Complex Integrin Alpha3-beta1 Complex Integrin Complex Formation Of Radial Glial Scaffolds Cell-matrix Adhesion Integrin-mediated Signaling Pathway Mesodermal Cell Differentiation Laminin Binding Negative Regulation Of Rho Protein Signal Transduction Cell-substrate Adhesion Myoblast Fusion Fibronectin Binding Receptor Complex Syncytium Formation By Plasma Membrane Fusion Cell-cell Fusion Syncytium Formation Positive Regulation Of Cell Migration Positive Regulation Of Locomotion Positive Regulation Of Cell Motility Integrin Alpha6-beta4 Complex Myoblast Fate Specification Integrin Alpha7-beta1 Complex Inhibitory MHC Class Ib Receptor Activity Antibacterial Peptide Secretion Signaling Receptor Activity Cell Surface Negative Regulation Of Small GTPase Mediated Signal Transduction Synaptic Membrane Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Periphery Neuromuscular Junction Positive Regulation Of Glutamate Uptake Involved In Transmission Of Nerve Impulse Integrin Alpha8-beta1 Complex Integrin Alpha1-beta1 Complex Integrin Alpha5-beta1 Complex Integrin Alpha10-beta1 Complex Integrin Alphav-beta1 Complex Integrin Alpha11-beta1 Complex Cardiac Cell Fate Specification Integrin Alpha9-beta1 Complex HLA-E Specific Inhibitory MHC Class Ib Receptor Activity External Side Of Plasma Membrane Positive Regulation Of GTPase Activity Growth Cone Filopodium Regulation Of Rho Protein Signal Transduction Positive Regulation Of Protein Localization To Membrane Integrin Alpha4-beta1 Complex Integrin Alpha2-beta1 Complex Natural Killer Cell Inhibitory Signaling Pathway CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation