SLC35E3 and SELENOK

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		SLC35E3	SELENOK
Name		solute carrier family 35 member E3	selenoprotein K
Structure		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane
	Molecular Function	Nucleotide-sugar Transmembrane Transporter Activity Protein Binding Antiporter Activity	Protein Binding Identical Protein Binding
	Biological Process	Organophosphate Ester Transport Nucleobase-containing Compound Transport Transmembrane Transport Carbohydrate Derivative Transport	Positive Regulation Of Defense Response To Virus By Host Monoatomic Ion Transport Calcium Ion Transport Response To Oxidative Stress Macrophage Derived Foam Cell Differentiation Protein Palmitoylation Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production T Cell Proliferation Positive Regulation Of T Cell Proliferation Respiratory Burst After Phagocytosis Regulation Of Calcium-mediated Signaling Regulation Of Protein Transport Establishment Of Localization In Cell Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Positive Regulation Of Monocyte Chemotactic Protein-1 Production T Cell Migration Positive Regulation Of Neutrophil Migration Neutrophil Migration Positive Regulation Of T Cell Migration
GWAS		Mean reticulocyte volume ( 32888494 ) White blood cell count ( 20139978 )	No GWAS studies recorded
Interacting Genes		23 interacting genes: ADIPOQ ARLN ATP6V0C BCL2L2 BIK BNIP2 CSGALNACT2 FAM209A FFAR2 FXYD6 GET1 GPR25 LNPEP PLP1 RUSF1 SELENOK SLC66A2 SPG21 SSMEM1 TMEM14B TMEM234 TMEM60 TTPA	42 interacting genes: AMIGO1 AQP6 BIK C6orf47 CLN8 CNR2 COMT CPLX4 CREB3 ERBB2 ERBB3 ERBB4 ERGIC3 FAM209A FFAR2 FKBP7 GLP1R GORAB GPR35 GPX8 IL10RA KLHDC2 LMNA MFSD6 MMD MRM1 MTIF3 MUC1 REEP4 RNF19B SAR1A SLC10A1 SLC10A6 SLC18A1 SLC30A8 SLC35E3 SLC35H1 STMN4 STOM TMEM31 TMPRSS2 TMX2
Entrez ID		55508	58515
HPRD ID		15375	07448
Ensembl ID		ENSG00000175782	ENSG00000113811
Uniprot IDs		Q7Z769	Q9Y6D0
PDB IDs		Not available	6DO3
GO Terms Enriched among Interactors		Membrane Bcl-2 Family Protein Complex Positive Regulation Of Chemokine Production Positive Regulation Of Monocyte Chemotactic Protein-1 Production	Membrane ERBB3:ERBB2 Complex Neuregulin Receptor Activity ERBB2 Signaling Pathway ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Bile Acid:sodium Symporter Activity Norepinephrine Transport ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway