SEMA3F

Name	semaphorin 3F
Structure	No pdb structure
Novel Interactors	1 novel interactors: FBN2
Interactors	7 interactors: NRP1 NRP2 SHBG SLC35G2 UBA1 UBC VEGFA
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Glutamatergic Synapse
	Molecular Function	Signaling Receptor Binding Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity
	Biological Process	Neural Crest Cell Migration Signal Transduction Axon Guidance Facial Nerve Structural Organization Trigeminal Nerve Structural Organization Nerve Development Branchiomotor Neuron Axon Guidance Positive Regulation Of Cell Migration Trunk Neural Crest Cell Migration Ventral Trunk Neural Crest Cell Migration System Development Negative Regulation Of Axon Extension Involved In Axon Guidance Axon Extension Involved In Axon Guidance Negative Chemotaxis Sympathetic Ganglion Development Semaphorin-plexin Signaling Pathway Sympathetic Neuron Projection Extension Sympathetic Neuron Projection Guidance Regulation Of Postsynapse Organization Neural Crest Cell Migration Involved In Autonomic Nervous System Development
GWAS	Age at first birth ( 27089180 ) Age at first sexual intercourse ( 34211149 27089180 ) Body mass index ( 29273807 26426971 ) Brain morphology (min-P) ( 32665545 ) Brain morphology (MOSTest) ( 32665545 ) Cortical surface area (MOSTest) ( 32665545 ) Extremely high intelligence ( 29520040 ) General cognitive ability ( 29844566 ) General risk tolerance (MTAG) ( 30643258 ) Glaucoma ( 31959993 ) High light scatter reticulocyte count ( 32888494 ) High light scatter reticulocyte percentage of red cells ( 32888494 ) Household income (MTAG) ( 31844048 ) Intelligence (MTAG) ( 29326435 ) Intraocular pressure ( 31959993 29785010 ) Lateral thalamic nuclei volume ( 34006833 ) Mean platelet volume ( 32888494 ) Morning person ( 30696823 ) Multisite chronic pain ( 33830993 ) Refractive error ( 32231278 ) Regular attendance at a gym or sports club ( 29970889 ) Reticulocyte count ( 32888494 ) Reticulocyte fraction of red cells ( 32888494 ) Sleep duration (short sleep) ( 30846698 ) Smoking initiation ( 33082346 ) Subcortical volume (min-P) ( 32665545 ) Subcortical volume (MOSTest) ( 32665545 )
Entrez ID	6405
HPRD ID	03079
Ensembl ID	ENSG00000001617
Uniprot IDs	C9JPG5 Q13275 Q59G50
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Vascular Endothelial Growth Factor Signaling Pathway VEGF-activated Neuropilin Signaling Pathway Vestibulocochlear Nerve Structural Organization Dorsal Root Ganglion Morphogenesis Sensory Neuron Axon Guidance Facioacoustic Ganglion Development Ventral Trunk Neural Crest Cell Migration Neuropilin Signaling Pathway Sympathetic Neuron Projection Guidance Trigeminal Ganglion Development Cranial Ganglion Development Trunk Neural Crest Cell Migration Positive Regulation Of Axon Extension Involved In Axon Guidance Trigeminal Nerve Structural Organization Neural Crest Cell Migration Involved In Autonomic Nervous System Development Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Sympathetic Neuron Projection Extension Vascular Endothelial Growth Factor Receptor Activity Branchiomotor Neuron Axon Guidance Bone Trabecula Formation Hypothalamus Cell Migration Coronary Artery Morphogenesis Facial Nerve Structural Organization Sympathetic Ganglion Development Positive Regulation Of Endothelial Cell Proliferation Coronary Vasculature Morphogenesis Endothelial Cell Chemotaxis Axon Extension Involved In Axon Guidance Motor Neuron Migration Semaphorin Receptor Activity Commissural Neuron Axon Guidance Positive Regulation Of Endothelial Cell Migration Semaphorin Receptor Complex Regulation Of Axon Extension Involved In Axon Guidance Ganglion Development Regulation Of Trophoblast Cell Migration Anatomical Structure Arrangement Neuron Migration Regulation Of Endothelial Cell Proliferation Retinal Ganglion Cell Axon Guidance Heparin Binding Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Motor Neuron Axon Guidance Outflow Tract Septum Morphogenesis Regulation Of Endothelial Cell Migration Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Epithelial Cell Proliferation Branching Involved In Blood Vessel Morphogenesis