STRADB

Name	STE20 related adaptor beta
Structure	No pdb structure
Novel Interactors	3 novel interactors: COQ10B PPIL3 SF3B1
Interactors	8 interactors: CAB39 GRB2 MAP3K7 NEB STK11 TRAF6 UBC XIAP
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Aggresome Serine/threonine Protein Kinase Complex
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Binding ATP Binding Protein Serine/threonine Kinase Activator Activity
	Biological Process	Cell Morphogenesis Protein Phosphorylation Protein Export From Nucleus JNK Cascade Activation Of Protein Kinase Activity Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways	Energy dependent regulation of mTOR by LKB1-AMPK
GWAS	No GWAS studies recorded
Entrez ID	55437
HPRD ID	09546
Ensembl ID	ENSG00000082146
Uniprot IDs	Q9C0K7
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Protein Serine/threonine Kinase Binding Immune Response-activating Signaling Pathway Antigen Receptor-mediated Signaling Pathway Immune Response-regulating Signaling Pathway Activation Of Immune Response Canonical NF-kappaB Signal Transduction Interleukin-17A-mediated Signaling Pathway Interleukin-33-mediated Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Type I Interferon Production Immune Response-regulating Cell Surface Receptor Signaling Pathway Anoikis Positive Regulation Of JUN Kinase Activity TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Immune Response Negative Regulation Of Canonical NF-kappaB Signal Transduction Cytoplasmic Pattern Recognition Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway T Cell Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Protein Modification Process DNA Damage Response Regulation Of Type I Interferon Production Positive Regulation Of Kinase Activity Positive Regulation Of Protein Kinase Activity Serine/threonine Protein Kinase Complex Stimulatory C-type Lectin Receptor Signaling Pathway Cellular Response To Lectin Fc-epsilon Receptor Signaling Pathway P38MAPK Cascade Regulation Of Innate Immune Response Interleukin-1-mediated Signaling Pathway Endolysosomal Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Positive Regulation Of T Cell Cytokine Production Innate Immune Response-activating Signaling Pathway Regulation Of Immune Response Cellular Response To Stress Non-canonical NF-kappaB Signal Transduction Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of MAP Kinase Activity Positive Regulation Of Immune System Process Positive Regulation Of Interleukin-2 Production Activation Of Innate Immune Response Activation Of Protein Kinase Activity Regulation Of T Cell Cytokine Production Protein Kinase Activator Activity Toll-like Receptor 4 Signaling Pathway