ATP12A

Name	ATPase H+/K+ transporting non-gastric alpha2 subunit
Structure	No pdb structure
Interactors	3 interactors: GNAI3 NPY PPIB
GO Annotations	Cellular Component	Cytosol Plasma Membrane Potassium:proton Exchanging ATPase Complex Actin Cytoskeleton Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cation-transporting ATPase Complex Plasma Membrane Protein Complex
	Molecular Function	Nucleotide Binding P-type Sodium:potassium-exchanging Transporter Activity ATP Binding P-type Potassium Transmembrane Transporter Activity P-type Potassium:proton Transporter Activity ATP Hydrolysis Activity Metal Ion Binding
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Intracellular Sodium Ion Homeostasis Regulation Of PH Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Intracellular Potassium Ion Homeostasis Sodium Ion Export Across Plasma Membrane Potassium Ion Homeostasis Proton Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways	Ion transport by P-type ATPases
GWAS	Diastolic blood pressure ( 30224653 ) Meconium ileus in cystic fibrosis ( 30807572 ) Obesity-related traits ( 23251661 )
Entrez ID	479
HPRD ID	01667
Ensembl ID	ENSG00000075673
Uniprot IDs	B4E0R9 P54707
PDB IDs	Not available
GO Terms Enriched among Interactors ?	G Protein-coupled Receptor Binding Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Y Receptor Binding Monocyte Activation Positive Regulation Of Eating Behavior Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Regulation Of Eating Behavior Positive Regulation Of Response To Food Short-day Photoperiodism Regulation Of Nerve Growth Factor Production Positive Regulation Of Dopamine Metabolic Process Antifungal Humoral Response Positive Regulation Of Appetite Synaptic Signaling Via Neuropeptide Intestinal Epithelial Cell Differentiation Adult Feeding Behavior Positive Regulation Of Feeding Behavior Cyclosporin A Binding Endoplasmic Reticulum Chaperone Complex Host-mediated Perturbation Of Viral Genome Replication Host-mediated Activation Of Viral Genome Replication Negative Regulation Of Acute Inflammatory Response Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Response To Yeast Guanyl Nucleotide Binding Regulation Of Response To Food Regulation Of Acute Inflammatory Response To Antigenic Stimulus G-protein Beta/gamma-subunit Complex Binding GTP Metabolic Process Regulation Of Dopamine Metabolic Process Neuronal Dense Core Vesicle Smooth Endoplasmic Reticulum RNA Polymerase Binding Regulation Of Appetite Regulation Of Feeding Behavior Photoperiodism Perinuclear Region Of Cytoplasm Positive Regulation Of Behavior Neuropeptide Hormone Activity Negative Regulation Of Inflammatory Response To Antigenic Stimulus Heterotrimeric G-protein Complex Positive Regulation Of Multicellular Organism Growth G Protein-coupled Receptor Signaling Pathway Regulation Of Response To Nutrient Levels Peptidyl-prolyl Cis-trans Isomerase Activity Host-mediated Activation Of Viral Process Terminal Bouton Positive Regulation Of Nitric Oxide Metabolic Process Calcium Channel Regulator Activity Central Nervous System Neuron Development