MSI1

Name	musashi RNA binding protein 1
Structure	No pdb structure
Interactors	27 interactors: APP HNRNPF HNRNPH2 MIR128-2 MIR15B MIR18A MIR19A MIR19B2 MIR20A MIR221 MIR29B1 MIR29B2 MIR29C MIR34B MIR34C MIR7-2 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7C MIRLET7D MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PNMA1
GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding Poly(U) RNA Binding Identical Protein Binding Protein Homodimerization Activity Molecular Condensate Scaffold Activity
	Biological Process	Regulation Of Translation Nervous System Development Central Nervous System Development Response To Hormone Epithelial Cell Differentiation
Pathways	Regulation of expression of SLITs and ROBOs
GWAS	Bipolar disorder ( 31043756 ) Hip circumference adjusted for BMI ( 34021172 ) Rheumatoid arthritis ( 30891314 ) Spontaneous preterm birth with premature rupture of membranes ( 31194736 ) Waist-to-hip ratio adjusted for BMI ( 28552196 )
Entrez ID	4440
HPRD ID	04509
Ensembl ID	ENSG00000135097
Uniprot IDs	O43347
PDB IDs	Not available
GO Terms Enriched among Interactors ?	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Extracellular Vesicle MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MRNA 3'-UTR Binding Negative Regulation Of Sprouting Angiogenesis Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Gene Expression MRNA Destabilization RNA Destabilization Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Positive Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Sprouting Angiogenesis Negative Regulation Of Translation Negative Regulation Of Signal Transduction Negative Regulation Of Extracellular Matrix Organization Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of MRNA Stability Regulation Of Metabolic Process Extracellular Space Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of RNA Stability Regulation Of Angiogenesis Negative Regulation Of Extracellular Matrix Assembly Regulation Of Vasculature Development Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Multicellular Organismal Process Regulation Of Translation Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Blood Vessel Endothelial Cell Migration