PSORS1C2

Name	psoriasis susceptibility 1 candidate 2
Structure	No pdb structure
Interactors	27 interactors: AGR2 AP1B1 AP2B1 BANP CEP70 ERICH2 EVPL GUCA1C HMG20A HOMER3 LHX3 MED20 MEIS3 MYL2 MYL7 NCKIPSD PAX6 PEX19 REL RTRAF SERTAD1 SGTA SGTB TTC23 UBQLN1 UBQLN2 VASP
GO Annotations	Cellular Component	Extracellular Region
	Molecular Function	Protein Binding
GWAS	Asthma ( 31619474 ) Asthma (childhood onset) ( 31619474 ) Asthma and major depressive disorder ( 31619474 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Broad depression or schizophrenia ( 30626913 ) Clostridioides difficle infection in antibiotics-users ( 33841421 ) Height ( 25282103 28552196 ) Hematology traits ( 23263863 ) Hip circumference adjusted for BMI ( 34021172 ) Inflammatory bowel disease ( 28067908 ) Malaria ( 31844061 ) Metabolite levels ( 23823483 ) Multiple myeloma ( 26007630 33875642 ) Multiple myeloma and monoclonal gammopathy ( 26007630 ) Night sleep phenotypes ( 27126917 ) Serum uric acid levels ( 30993211 ) Ulcerative colitis ( 28067908 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 ) White blood cell count ( 21738480 )
Entrez ID	170680
HPRD ID	17921
Ensembl ID	ENSG00000204538
Uniprot IDs	A0A1U9X9A6 Q9UIG4
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Positive Regulation Of Response To Endoplasmic Reticulum Stress TRC Complex Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Regulation Of Response To Endoplasmic Reticulum Stress Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Clathrin Adaptor Complex A Band Cell Fate Specification Protein Targeting Identical Protein Binding ERAD Pathway Response To Endoplasmic Reticulum Stress Heart Contraction Positive Regulation Of Proteasomal Protein Catabolic Process Clathrin Binding Membrane Coat Heart Process Muscle Cell Fate Specification Forebrain-midbrain Boundary Formation Pituitary Gland Development Pancreatic A Cell Development Negative Regulation Of Lipid Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Establishment Of Protein Localization To Endoplasmic Reticulum Protein Targeting To ER Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Store-operated Calcium Channel Activity