SYNPO

Name	synaptopodin
Structure	No pdb structure
Novel Interactors	2 novel interactors: G3BP1 NDST1
Interactors	9 interactors: CDC5L MAGI1 NCK1 NCK2 NONO NUFIP2 SGF29 YWHAG YWHAZ
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Bicellular Tight Junction Postsynaptic Density Actin Cytoskeleton Z Disc Cell Projection Dendritic Spine Perikaryon Organelle Synapse Anchoring Junction Spine Apparatus Glutamatergic Synapse
	Molecular Function	Actin Binding Protein Binding
	Biological Process	Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Stress Fiber Assembly Spine Apparatus Assembly
GWAS	Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025 ) Crohn's disease ( 28067908 ) Inflammatory bowel disease ( 28067908 ) Medication use (anti-inflammatory and antirheumatic products, non-steroids) ( 31015401 )
Entrez ID	11346
HPRD ID	12179
Ensembl ID	ENSG00000171992
Uniprot IDs	Q8N3V7
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Protein Sequestering Activity Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Protein Domain Specific Binding Response To Stress Positive Regulation Of Translation In Response To Stress Receptor Tyrosine Kinase Binding Signal Complex Assembly Cellular Response To Stress Regulation Of Translation In Response To Endoplasmic Reticulum Stress Regulation Of Translational Initiation In Response To Stress Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Translational Initiation Positive Regulation Of Cell-cell Adhesion Regulation Of PERK-mediated Unfolded Protein Response Negative Regulation Of Intracellular Signal Transduction Cytoskeletal Anchor Activity Regulation Of Translation In Response To Stress Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Signal Transduction Positive Regulation Of Translation Negative Regulation Of Cell Communication Negative Regulation Of Signaling RNA Binding Signaling Receptor Complex Adaptor Activity Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion Regulation Of Intrinsic Apoptotic Signaling Pathway Lamellipodium Assembly Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Unfolded Protein Response Vesicle Membrane Positive Regulation Of Response To Endoplasmic Reticulum Stress Lamellipodium Organization Response To Endoplasmic Reticulum Stress Positive Regulation Of Translational Initiation Positive Regulation Of Actin Filament Polymerization Molecular Condensate Scaffold Activity Cellular Response To Glucose Starvation Negative Regulation Of Response To Endoplasmic Reticulum Stress Ephrin Receptor Signaling Pathway Innate Immune Response Positive Regulation Of T Cell Activation Positive Regulation Of Gene Expression Positive Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Intracellular Signal Transduction Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process