GJC1

Name	gap junction protein gamma 1
Structure
Interactors	8 interactors: APOL3 CNST MEOX2 SLC66A1 TJP1 TJP3 TMEM86A UBQLN4
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Gap Junction Connexin Complex Intercalated Disc Membrane Synapse Anchoring Junction
	Molecular Function	Monoatomic Ion Channel Activity Gap Junction Channel Activity Protein Binding Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling
	Biological Process	Vasculogenesis Muscle Contraction Cell-cell Junction Assembly Cell Communication Cell-cell Signaling Chemical Synaptic Transmission Heart Development Visual Perception Gap Junction Assembly Monoatomic Ion Transmembrane Transport Cell Development Cardiac Muscle Tissue Development Transmembrane Transport Atrial Cardiac Muscle Cell Action Potential SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling
Pathways	Electric Transmission Across Gap Junctions Gap junction assembly
GWAS	No GWAS studies recorded
Entrez ID	10052
HPRD ID	08819
Ensembl ID	ENSG00000182963
Uniprot IDs	P36383
PDB IDs	3SHW
GO Terms Enriched among Interactors ?	Positive Regulation Of Blood-brain Barrier Permeability Regulation Of Blood-brain Barrier Permeability Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Vascular Permeability Protein Localization To Cell-cell Junction Maintenance Of Blood-brain Barrier Tight Junction Establishment Of Endothelial Barrier Endothelial Cell Development Regulation Of Vascular Permeability Protein Localization To Cell Junction Cell Adhesion Molecule Binding Lysine Transport Nuclear Proteasome Complex Alkenylglycerophosphocholine Hydrolase Activity Bicellular Tight Junction Negative Regulation Of Autophagosome Maturation Epithelial Cell Development Somite Specification Protein Localization To Bicellular Tight Junction Adherens Junction Maintenance Protein Localization To Adherens Junction L-lysine Transmembrane Transport L-lysine Transmembrane Transporter Activity L-histidine Transmembrane Transporter Activity L-histidine Transmembrane Transport Cytosolic Proteasome Complex Positive Regulation Of Golgi To Plasma Membrane Protein Transport Connexin Binding Cell-cell Junction Organization Anatomical Structure Homeostasis Tissue Homeostasis Ameloblast Differentiation Cell Junction Protein-containing Complex Basic Amino Acid Transmembrane Transporter Activity Intracellular Amino Acid Homeostasis L-arginine Transmembrane Transporter Activity Aromatic Amino Acid Transport K48-linked Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin L-arginine Transmembrane Transport Regulation Of Golgi To Plasma Membrane Protein Transport Azole Transmembrane Transport Vascular Process In Circulatory System