SH2D3A

Name	SH2 domain containing 3A
Structure	No pdb structure
Novel Interactors	2 novel interactors: ITGB8 RRM1
Interactors	7 interactors: BCAR1 CENPB EGFR ERBB2 ERBB3 GAB1 NXF1
GO Annotations	Molecular Function	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	JNK Cascade Small GTPase-mediated Signal Transduction
GWAS	No GWAS studies recorded
Entrez ID	10045
HPRD ID	05283
Ensembl ID	ENSG00000125731
Uniprot IDs	A8K2M8 Q9BRG2
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway ERBB2 Signaling Pathway ERBB3:ERBB2 Complex Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway ErbB-3 Class Receptor Binding Basal Plasma Membrane ERBB2-EGFR Signaling Pathway ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Protein Tyrosine Kinase Activator Activity Protein Tyrosine Kinase Activity Schwann Cell Development Peripheral Nervous System Development Receptor Complex Positive Regulation Of Epithelial Cell Proliferation Cell Surface Receptor Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Transmembrane Signaling Receptor Activity Basolateral Plasma Membrane Growth Factor Binding Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Transmembrane Receptor Protein Tyrosine Kinase Activity Response To Epidermal Growth Factor Cellular Response To Growth Factor Stimulus Animal Organ Development Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Cell Cycle G1/S Phase Transition Response To Growth Factor Multivesicular Body, Internal Vesicle Lumen Regulation Of Angiogenesis Glial Cell Development Ribonucleoside-diphosphate Reductase Activity Regulation Of Vasculature Development Wound Healing Neuron Differentiation Cell Migration Insulin Receptor Signaling Pathway Regulation Of Epithelial Cell Proliferation Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Growth Ruffle Membrane Focal Adhesion Shc-EGFR Complex Myelination Axon Ensheathment Positive Regulation Of Cardiac Muscle Tissue Development