PTBP3 and MIR25

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		PTBP3	MIR25
Description		polypyrimidine tract binding protein 3	microRNA 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Space RISC Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding	MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	MRNA Processing RNA Splicing Anatomical Structure Morphogenesis Cell Differentiation Negative Regulation Of RNA Splicing Erythrocyte Maturation Regulation Of RNA Splicing Regulation Of Cell Differentiation	MiRNA-mediated Post-transcriptional Gene Silencing Negative Regulation Of Cardiac Muscle Tissue Growth Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Pathways
Drugs
Diseases
GWAS		Obstetric antiphospholipid syndrome ( 28424481) Panic disorder ( 31712720)
Interacting Genes		60 interacting genes: APP CD2BP2 LINC00624 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7C RBPMS SLC25A21-AS1	100 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC5L CELF1 CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 ELAC1 EPRS1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PATL1 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA PURB QARS1 RARS1 RBFOX2 RBM14 RBM17 RBM4 RBM45 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM25 TRIM56 TRIM71 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3
Entrez ID		9991	407014
HPRD ID		09603
Ensembl ID		ENSG00000119314	ENSG00000207547
Uniprot IDs		O95758
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity RISC Complex Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Negative Regulation Of Cytokine Production Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Multicellular Organismal Process Regulation Of Angiogenesis Regulation Of Vasculature Development MRNA Destabilization Negative Regulation Of Vascular Endothelial Growth Factor Production RNA Destabilization Regulation Of Gene Expression Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Cell Migration Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Developmental Process Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of Translation Regulation Of Macromolecule Metabolic Process Positive Regulation Of MRNA Metabolic Process Extracellular Space Regulation Of Cytokine Production Regulation Of Metabolic Process Regulation Of MRNA Stability Negative Regulation Of Protein Metabolic Process Regulation Of RNA Stability Regulation Of Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Endothelial Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Negative Regulation Of Signal Transduction Regulation Of Vascular Endothelial Growth Factor Production Regulation Of MRNA Metabolic Process	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process MRNA Metabolic Process RNA Splicing MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome Nucleus RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Nucleoplasm Post-transcriptional Regulation Of Gene Expression Aminoacyl-tRNA Synthetase Multienzyme Complex Spliceosomal Complex Ribonucleoprotein Complex Catalytic Step 2 Spliceosome Cytoplasmic Stress Granule Regulation Of Translation MiRNA Binding Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Negative Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of RNA Stability Regulation Of MRNA Stability Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Catabolic Process Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Metabolic Process TRNA Aminoacylation Ligase Activity MRNA Stabilization Negative Regulation Of Metabolic Process P-body
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