KIAA0753 and ZNF114

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KIAA0753	ZNF114
Description		KIAA0753	zinc finger protein 114
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton Cilium Centriolar Satellite Ciliary Basal Body	Nucleus Extracellular Exosome
	Molecular Function	Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Centriole Replication Cilium Assembly Cytosolic Ciliogenesis Protein Localization To Centrosome	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Familial lung cancer ( 29924316) LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Pulse pressure ( 27841878 28135244 30578418) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		20 interacting genes: AARD AIRIM BHLHA9 BRPF1 CCHCR1 CT55 FAM161A GCC1 HGS KIFC3 MNS1 RNF6 ROPN1 SMARCD1 SUOX TCHP TEAD4 USHBP1 ZNF114 ZNF777	10 interacting genes: CENATAC CLIP4 KIAA0753 KLHL2 KRTAP10-6 MAP7 MYO15B SUFU TPPP ZNF8
Entrez ID		9851	163071
HPRD ID		11106	14463
Ensembl ID		ENSG00000198920	ENSG00000178150
Uniprot IDs		Q2KHM9	Q8NC26
PDB IDs
Enriched GO Terms of Interacting Partners?		Polymeric Cytoskeletal Fiber	Cytoskeleton Microtubule-based Process Postsynaptic Golgi Apparatus Cytoplasmic Microtubule Organization Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Regulation Of Cellular Response To Drug Positive Regulation Of Cellular Response To Drug Positive Regulation Of Response To Drug Microtubule Organizing Center
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