SLK and CLSTN1

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SLK	CLSTN1
Gene Name		STE20-like kinase	calsyntenin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Extracellular Vesicular Exosome	Golgi Membrane Nucleus Endoplasmic Reticulum Membrane Integral Component Of Membrane Cell Junction Cell Projection Postsynaptic Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity ATP Binding Identical Protein Binding Protein Homodimerization Activity	Beta-amyloid Binding Calcium Ion Binding Protein Binding Kinesin Binding X11-like Protein Binding
	Biological Process	Apoptotic Process Signal Transduction By Phosphorylation Intracellular Signal Transduction Protein Autophosphorylation	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Pathways
Drugs
Diseases
GWAS		Uterine fibroids ( 21460842)
Protein-Protein Interactions		3 interactors: CASP3 CLSTN1 PDZK1	14 interactors: APBA2 APBB1 BAHCC1 COL17A1 KIF2A KLC1 KLC2 MCM3AP MDM2 PRNP SETDB1 SLK TOPBP1 TRIP12
Entrez ID		9748	22883
HPRD ID		11585	10837
Ensembl ID		ENSG00000065613	ENSG00000171603
Uniprot IDs		Q9H2G2	B3KMD3 B4E3Q1 O94985
PDB IDs		2J51 2JFL 2JFM 2UV2
Enriched GO Terms of Interacting Partners?		Glial Cell Apoptotic Process Regulation Of Apoptotic DNA Fragmentation Carnitine Transport Negative Regulation Of Activated T Cell Proliferation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Negative Regulation Of B Cell Proliferation Quaternary Ammonium Group Transport Apoptotic DNA Fragmentation Platelet Formation Platelet Morphogenesis Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Hippo Signaling Release Of Cytochrome C From Mitochondria Apoptotic Nuclear Changes Positive Regulation Of Protein Targeting To Membrane Regulation Of Activated T Cell Proliferation B Cell Homeostasis T Cell Homeostasis Negative Regulation Of B Cell Activation	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Response To DNA Damage Stimulus Response To Stress Antigen Processing And Presentation Of Peptide Antigen Axon Cargo Transport Peptidyl-lysine Modification Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Antigen Processing And Presentation Regulation Of DNA Repair Cellular Response To UV-C Cellular Response To Vitamin B1 Negative Regulation Of Thymidylate Synthase Biosynthetic Process Microtubule-based Movement Movement Of Cell Or Subcellular Component Cellular Response To DNA Damage Stimulus Stress Granule Disassembly Negative Regulation Of Protein Metabolic Process Blood Coagulation Negative Regulation Of Histone H2A K63-linked Ubiquitination Hemostasis Negative Regulation Of Cell Cycle Response To Radiation Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Traversing Start Control Point Of Mitotic Cell Cycle Negative Regulation Of Calcineurin-NFAT Signaling Cascade Cell Cycle Process Microtubule-based Transport DNA Metabolic Process Cytoskeleton-dependent Intracellular Transport Response To Vitamin B1 Response To Ether Cell Cycle Arrest Cellular Component Assembly Cellular Response To Copper Ion Regulation Of Protein K63-linked Ubiquitination Negative Regulation Of Double-strand Break Repair Negative Regulation Of Calcium-mediated Signaling Regulation Of Body Fluid Levels Behavior Protein Localization To Nucleus Negative Regulation Of DNA Repair DNA Repair Chromatin Modification Wound Healing Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Interleukin-17 Production Histone H3-K9 Trimethylation
Tagcloud ?		chorionic commercial complementary crude deoxynucleotidyl deoxyuridine digoxigenin exhibiting fractions furthered go gonadotropin haf hcg immunodeficiency inoculation kaposi ks neoplastic nick preceded pregnancy preparations rel sarcoma transferase triphosphate tunel y	adhesion adhesive atypical bead broad cadherin caenorhabditis calsyntenin calsyntenins characterizing cloned diffusible ectodomains elegans heterophilic homophilic idea mediate mediates members nervous preferences repeats sorting superfamily vertebrate zebrafish
Tagcloud (Difference) ?		chorionic commercial complementary crude deoxynucleotidyl deoxyuridine digoxigenin exhibiting fractions furthered go gonadotropin haf hcg immunodeficiency inoculation kaposi ks neoplastic nick preceded pregnancy preparations rel sarcoma transferase triphosphate tunel y	adhesion adhesive atypical bead broad cadherin caenorhabditis calsyntenin calsyntenins characterizing cloned diffusible ectodomains elegans heterophilic homophilic idea mediate mediates members nervous preferences repeats sorting superfamily vertebrate zebrafish
Tagcloud (Intersection) ?