CROCC and RNF152

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CROCC	RNF152
Description		ciliary rootlet coiled-coil, rootletin	ring finger protein 152
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Inner Segment Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Plasma Membrane Cilium Actin Cytoskeleton Ciliary Rootlet Ciliary Basal Body Cell Projection Extracellular Exosome Glial Cell Projection 9+2 Motile Cilium Subapical Part Of Cell	Lysosome Lysosomal Membrane Membrane Organelle Membrane
	Molecular Function	Actin Binding Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Kinesin Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Small GTPase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Centrosome Cycle Intracellular Protein Localization Centriole-centriole Cohesion Epithelial Structure Maintenance Cellular Homeostasis Cell Projection Organization Ciliary Basal Body Organization Protein Localization To Organelle Photoreceptor Cell Maintenance Positive Regulation Of Cilium Assembly Establishment Of Localization In Cell Establishment Of Organelle Localization Positive Regulation Of Protein Localization To Cilium	Protein Polyubiquitination Cytoplasmic Translation Protein Monoubiquitination Apoptotic Process Cellular Response To Starvation Positive Regulation Of Autophagy Protein Ubiquitination Cellular Response To Nutrient Levels Cellular Response To Amino Acid Starvation TORC1 Signaling Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Protein Localization To Lysosome Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Negative Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling Response To Amino Acid Starvation
Pathways			E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Allergic rhinitis ( 22036096) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Hematocrit ( 32888494) Lymphocyte percentage of white cells ( 32888494) Red blood cell count ( 32888494) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 28552196 34021172) Waist-hip index ( 34021172)	Estimated glomerular filtration rate ( 30604766 31015462) Glomerular filtration rate (creatinine) ( 26831199 28452372)
Interacting Genes		2 interacting genes: KLC3 RNF152	12 interacting genes: CROCC EBP GJA8 KIR2DL3 MYD88 RHEB TRAF6 TSPAN12 UBE2E1 UBE2N UBE2W UBE3A
Entrez ID		9696	220441
HPRD ID		16758	11514
Ensembl ID		ENSG00000058453	ENSG00000176641
Uniprot IDs		Q5TZA2	Q8N8N0
PDB IDs		6L5H 6L5J
Enriched GO Terms of Interacting Partners?			Regulation Of TORC1 Signaling Ubiquitin-protein Transferase Activity Protein Polyubiquitination Ubiquitin Conjugating Enzyme Activity Regulation Of TOR Signaling Response To Virus Protein Monoubiquitination Interleukin-33-mediated Signaling Pathway TORC1 Signaling Negative Regulation Of TORC1 Signaling Positive Regulation Of NF-kappaB Transcription Factor Activity TOR Signaling Cellular Response To Nutrient Levels Antiviral Innate Immune Response Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Negative Regulation Of TOR Signaling Defense Response To Virus MyD88-dependent Toll-like Receptor Signaling Pathway Protein K48-linked Ubiquitination Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Positive Regulation Of DNA-binding Transcription Factor Activity Protein Modification By Small Protein Conjugation Positive Regulation Of Post-translational Protein Modification Endolysosomal Toll-like Receptor Signaling Pathway Interleukin-1-mediated Signaling Pathway Immune Response-regulating Signaling Pathway Non-canonical NF-kappaB Signal Transduction Post-translational Protein Modification Regulation Of DNA-binding Transcription Factor Activity Tissue Homeostasis Anatomical Structure Homeostasis Lipopolysaccharide-mediated Signaling Pathway Response To Nutrient Levels Regulation Of Protein Ubiquitination Toll-like Receptor 4 Signaling Pathway Cell Surface Toll-like Receptor Signaling Pathway TIR Domain Binding Toll Binding ATP-dependent Histone Chaperone Activity Positive Regulation Of Canonical NF-kappaB Signal Transduction Induced Systemic Resistance Intracellular Receptor Signaling Pathway Cell Surface Pattern Recognition Receptor Signaling Pathway Toll-like Receptor Signaling Pathway Regulation Of Post-translational Protein Modification Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Sperm Entry Positive Regulation Of Golgi Lumen Acidification
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