LMOD1

Description		leiomodin 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Striated Muscle Thin Filament Actin Filament Membrane Myofibril Sarcomere
	Molecular Function	Actin Binding Tropomyosin Binding
	Biological Process	Muscle Contraction Actin Filament Organization Myofibril Assembly Positive Regulation Of Actin Filament Polymerization Actin Nucleation Pointed-end Actin Filament Capping
Pathways		Smooth Muscle Contraction
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Body mass index ( 28448500 28892062 29273807) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Breast size ( 27182965) Coronary artery disease ( 29212778 33020668) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Lung function (FEV1/FVC) ( 30804560) Sleep duration (short sleep) ( 30846698)
Novel Interacting Genes		1 novel interacting genes: IQCB1
Interacting Genes		1 interacting genes: ACTB
Entrez ID		25802
HPRD ID		04093
Ensembl ID		ENSG00000163431
Uniprot IDs		P29536
PDB IDs		4Z79 4Z8G 4Z94
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Regulation Of Norepinephrine Uptake BBSome Binding Regulation Of Transepithelial Transport Protein Localization To Adherens Junction Dense Body Transporter Regulator Activity Morphogenesis Of A Polarized Epithelium Maintenance Of Animal Organ Identity Cytosolic Ciliogenesis Structural Constituent Of Postsynaptic Actin Cytoskeleton Nitric-oxide Synthase Regulator Activity BBAF Complex Tat Protein Binding Postsynaptic Actin Cytoskeleton Brahma Complex Nitric-oxide Synthase Binding NBAF Complex Apical Protein Localization RSC-type Complex Adherens Junction Assembly Negative Regulation Of Cell Differentiation Postsynaptic Actin Cytoskeleton Organization NpBAF Complex GBAF Complex Protein Localization To Cell-cell Junction Calyx Of Held Postsynaptic Cytoskeleton Organization Regulation Of Synaptic Vesicle Endocytosis Regulation Of Nucleotide-excision Repair Negative Regulation Of Developmental Process Apical Junction Complex Cortical Cytoskeleton NuA4 Histone Acetyltransferase Complex Regulation Of Synaptic Vesicle Recycling SWI/SNF Complex Maintenance Of Blood-brain Barrier Cell Projection Organization Regulation Of G0 To G1 Transition Tight Junction Nucleosomal DNA Binding Photoreceptor Cell Maintenance Kinesin Binding Substantia Nigra Development Tau Protein Binding Photoreceptor Connecting Cilium Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Myoblast Differentiation Platelet Aggregation
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