WTAP and ZNF239

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		WTAP	ZNF239
Description		WT1 associated protein	zinc finger protein 239
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Nuclear Membrane RNA N6-methyladenosine Methyltransferase Complex	Nucleus
	Molecular Function	Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing MRNA Modification	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression
Pathways		Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS		Erosive tooth wear (severe vs non-severe) ( 29898447) Iron status biomarkers ( 19084217)
Interacting Genes		19 interacting genes: ABHD15 BYSL CPNE1 EIF4ENIF1 EXOSC4 GTSE1 MAGEA11 OGT PSMA1 SLIRP SNCA TAB1 TCF12 TNIP1 VPS52 WT1 YWHAQ ZNF239 ZNF572	6 interacting genes: CARD10 CEP70 KRTAP10-6 LMNA MTUS2 WTAP
Entrez ID		9589	8187
HPRD ID		09259	03044
Ensembl ID		ENSG00000146457	ENSG00000196793
Uniprot IDs		A0A087X1R4 Q15007	Q16600
PDB IDs		7VF2 7VF5 7YFJ 7YG4
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Gene Expression Cytosol Regulation Of Macromolecule Metabolic Process Nucleus Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Nucleoplasm Cytoplasm Regulation Of Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Embryonic Ectodermal Digestive Tract Development Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Catabolic Process Negative Regulation Of Translation Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Short-chain Carboxylesterase Activity Regulation Of Neuron Differentiation Positive Regulation Of Gene Expression Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Negative Regulation Of Mitochondrial MRNA Catabolic Process Negative Regulation Of Mitochondrial RNA Catabolic Process
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