SEC22B and B3GAT3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SEC22B	B3GAT3
Gene Name		SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)	beta-1,3-glucuronyltransferase 3
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome	Golgi Membrane Golgi Apparatus Cis-Golgi Network Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Syntaxin Binding	Protein Binding Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Activity Glucuronosyltransferase Activity Metal Ion Binding Protein Phosphatase Activator Activity
	Biological Process	ER To Golgi Vesicle-mediated Transport Protein Transport Regulation Of Organelle Organization Positive Regulation Of Protein Catabolic Process	Carbohydrate Metabolic Process Glycosaminoglycan Biosynthetic Process Protein Glycosylation Pathogenesis Heparan Sulfate Proteoglycan Biosynthetic Process Glycosaminoglycan Metabolic Process Chondroitin Sulfate Metabolic Process Positive Regulation Of Catalytic Activity Small Molecule Metabolic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Intracellular Protein Transport
Pathways			MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Heparan sulfate/heparin (HS-GAG) metabolism Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Chondroitin sulfate/dermatan sulfate metabolism Defective SLC26A2 causes chondrodysplasias Glycosaminoglycan metabolism Defective CHST14 causes EDS, musculocontractural type Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Defective CHST6 causes MCDC1 Glycogen storage diseases MPS IIID - Sanfilippo syndrome D A tetrasaccharide linker sequence is required for GAG synthesis MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A MPS IV - Morquio syndrome B Defective CHSY1 causes TPBS MPS VII - Sly syndrome Metabolism of carbohydrates MPS VI - Maroteaux-Lamy syndrome
Drugs			Udp-Glucuronic Acid Uridine-5\'-Diphosphate
Diseases
GWAS
Protein-Protein Interactions		2 interactors: B3GAT3 STX5	2 interactors: HNRNPD SEC22B
Entrez ID		9554	26229
HPRD ID		04939	07564
Ensembl ID			ENSG00000149541
Uniprot IDs		O75396	B7ZAB3 O94766
PDB IDs		2NUP 2NUT 3EGD 3EGX	1FGG 1KWS 3CU0
Enriched GO Terms of Interacting Partners?		Golgi Disassembly Golgi Inheritance Regulation Of Golgi Organization Vesicle Fusion With Golgi Apparatus Early Endosome To Golgi Transport Dermatan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Metabolic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Heparan Sulfate Proteoglycan Biosynthetic Process Heparan Sulfate Proteoglycan Metabolic Process Organelle Disassembly Vesicle Fusion Proteoglycan Biosynthetic Process Chondroitin Sulfate Metabolic Process Retrograde Transport, Endosome To Golgi Organelle Fusion Golgi Organization Vesicle Docking Membrane Docking Glycosaminoglycan Biosynthetic Process ER To Golgi Vesicle-mediated Transport Proteoglycan Metabolic Process Membrane Fusion Positive Regulation Of Intracellular Protein Transport	Circadian Regulation Of Translation
Tagcloud ?		bundle coat compete copii dissociates ejected enclosed facilitates golgi golgin gtpases membrin monomeric opposed p115 preferences prefusion proceed rab rbet1 snare snarepin snares stably stemmed syntaxin tether tethering vesicles
Tagcloud (Difference) ?		bundle coat compete copii dissociates ejected enclosed facilitates golgi golgin gtpases membrin monomeric opposed p115 preferences prefusion proceed rab rbet1 snare snarepin snares stably stemmed syntaxin tether tethering vesicles
Tagcloud (Intersection) ?