MED20 and MED29

Number of citations of the paper that reports this interaction (PMID 14576168)
11

Data Source:
HPRD (in vitro)

		MED20	MED29
Gene Name		mediator complex subunit 20	mediator complex subunit 29
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mediator Complex	Nucleoplasm Mediator Complex
	Molecular Function	RNA Polymerase II Transcription Cofactor Activity DNA-directed RNA Polymerase Activity Protein Binding	Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 23263863 20139978) Red blood cell count ( 20139978)
Protein-Protein Interactions		7 interactors: CD300C ESR1 ESR2 MED18 MED29 MED8 POLR1B	9 interactors: MED1 MED12 MED13 MED14 MED17 MED20 MED21 MED9 USP47
Entrez ID		9477	55588
HPRD ID		15638	13748
Ensembl ID		ENSG00000124641	ENSG00000063322
Uniprot IDs		B3KUJ9 Q9H944	B4DUA7 Q9NX70
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA-templated Transcription, Initiation Transcription, DNA-templated Vagina Development Uterus Development RNA Biosynthetic Process Intracellular Estrogen Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Female Genitalia Development RNA Metabolic Process Prostate Gland Epithelium Morphogenesis Prostate Gland Morphogenesis Transcription From RNA Polymerase II Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Genitalia Development Ovarian Follicle Development Prostate Gland Development Intracellular Steroid Hormone Receptor Signaling Pathway Nucleologenesis Nucleobase-containing Compound Metabolic Process Ovulation Cycle Process Steroid Hormone Mediated Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Female Gonad Development Regulation Of Gene Expression Ovulation Cycle Development Of Primary Female Sexual Characteristics Cellular Nitrogen Compound Metabolic Process Hormone-mediated Signaling Pathway Prostate Epithelial Cord Elongation Nitrogen Compound Metabolic Process Gland Morphogenesis Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Epithelial Cell Maturation Involved In Prostate Gland Development Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Hormone-mediated Apoptotic Signaling Pathway Intracellular Receptor Signaling Pathway Epithelial Cell Development Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Branch Elongation Involved In Mammary Gland Duct Branching Antral Ovarian Follicle Growth Nucleolus Organization Gonad Development Development Of Primary Sexual Characteristics Female Pregnancy	Androgen Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Intracellular Steroid Hormone Receptor Signaling Pathway DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Stem Cell Maintenance Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Stem Cell Development Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Cell Differentiation Stem Cell Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Regulation Of Metabolic Process Axis Elongation Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Differentiation Cell Development Base-excision Repair Thyroid Hormone Mediated Signaling Pathway Positive Regulation Of Metabolic Process Cellular Metabolic Process Developmental Growth Involved In Morphogenesis Enucleate Erythrocyte Development Positive Regulation Of Interferon-gamma-mediated Signaling Pathway Positive Regulation Of G0 To G1 Transition Axis Elongation Involved In Somitogenesis Depyrimidination Regulation Of Organ Morphogenesis
Tagcloud ?		add cenp centromere centromeres centromeric cnp1 colocalizes defect desilencing directs dramatic fission heterochromatin incorporation kinetochore mediator mitosis ncrna ncrnas noncoding pericentromeric pol pombe rnai schizosaccharomyces segregation transcribed ultimately
Tagcloud (Difference) ?		add cenp centromere centromeres centromeric cnp1 colocalizes defect desilencing directs dramatic fission heterochromatin incorporation kinetochore mediator mitosis ncrna ncrnas noncoding pericentromeric pol pombe rnai schizosaccharomyces segregation transcribed ultimately
Tagcloud (Intersection) ?