MED29 and USP47

Number of citations of the paper that reports this interaction (PubMedID 14576168)
0

Data Source:
HPRD (in vitro)

		MED29	USP47
Description		mediator complex subunit 29	ubiquitin specific peptidase 47
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mediator Complex Core Mediator Complex	Nucleus Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Transcription Coregulator Activity Protein Binding	Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity WD40-repeat Domain Binding Deubiquitinase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II	DNA Repair Base-excision Repair Proteolysis DNA Damage Response Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Deubiquitination Regulation Of Protein Stability Monoubiquitinated Protein Deubiquitination Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions	Ub-specific processing proteases
Drugs
Diseases
GWAS			Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		11 interacting genes: ABI2 ABI3 BCAS2 CEBPA EIF2B1 MED14 MED20 MED9 NRDE2 SSC5D USP47	9 interacting genes: AP4M1 DSCR9 MED29 MED9 PLA2G2A RPS2 SNCA TLE3 UBC
Entrez ID		55588	55031
HPRD ID		13748	11668
Ensembl ID		ENSG00000063322	ENSG00000170242
Uniprot IDs		B4DUA7 Q9NX70	Q96K76
PDB IDs		7EMF 7ENA 7ENC 7ENJ 7LBM 8GXQ 8GXS 8T9D 8TQW 8TRH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation Core Mediator Complex Mediator Complex RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II Transcription Preinitiation Complex Assembly Actin-based Cell Projection Regulation Of Transcription Initiation By RNA Polymerase II SCAR Complex Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation Transcription Coregulator Activity Protein-DNA Complex Assembly Regulation Of Lamellipodium Assembly Regulation Of Dendritic Spine Morphogenesis Regulation Of Lamellipodium Organization Peptidyl-tyrosine Phosphorylation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Signaling Adaptor Activity Zonula Adherens Assembly Kinase Binding CHOP-C/EBP Complex White Fat Cell Proliferation Detection Of Bacterial Lipoprotein	Mitochondrial Outer Membrane Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Initiation By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Elongation By RNA Polymerase II Mediator Complex Core Mediator Complex Transcription Preinitiation Complex Assembly Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Elongation By RNA Polymerase II Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Protein Localization To Basolateral Plasma Membrane Regulation Of DNA-templated Transcription Elongation Phospholipid Binding Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake AP-4 Adaptor Complex Transcription Coregulator Activity Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process
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