CSNK1G3

Description		casein kinase 1 gamma 3
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Endocytosis Signal Transduction Wnt Signaling Pathway Protein Modification Process Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs		Purvalanol A {4-Amino-2-[(4-methoxyphenyl)amino]-1,3-thiazol-5-yl}(4-methoxyphenyl)methanone 4-Amino-2-[(3-chlorophenyl)amino]-5-(4-fluorobenzoyl)-1,3-thiazol-3-ium K-00546
Diseases
GWAS		Adult asthma ( 27611488) Amyotrophic lateral sclerosis ( 19451621) Apolipoprotein B levels ( 32203549) Cholesterol, total ( 24097068) Chronotype ( 30696823) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Diastolic blood pressure ( 30578418 27618452) Heel bone mineral density ( 30598549 28869591) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 28334899 32203549) Low density lipoprotein cholesterol levels ( 32154731) Metabolite levels ( 23823483) Nickel levels ( 26025379) Pulse pressure ( 27618448) Rapid response to perioperative phenylephrine (change in systolic blood pressure) ( 33168928) Red cell distribution width ( 32888494) Systolic blood pressure ( 27618452) Total body bone mineral density ( 29304378) Total cholesterol levels ( 28334899) Virologic severity in Herpes simplex virus type 2 infection ( 29535370)
Interacting Genes		7 interacting genes: CLSPN DBNDD2 DRICH1 KRTAP10-10 MDFI PPP1R14A SNCA
Entrez ID		1456
HPRD ID		05034
Ensembl ID		ENSG00000151292
Uniprot IDs		A0A8V8TKT3 Q9Y6M4
PDB IDs		2CHL 2IZR 2IZS 2IZT 2IZU 4G16 4G17 4HGL 4HGS 6GRO
Enriched GO Terms of Interacting Partners?		Protein Sequestering Activity Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Regulation Of Phosphorus Metabolic Process Transporter Regulator Activity Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake DNA Secondary Structure Binding Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process
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