ECEL1 and BRD2

		ECEL1	BRD2
Description		endothelin converting enzyme like 1	bromodomain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Chromatin Nucleus Nucleoplasm Chromosome Cytoplasm Nuclear Speck
	Molecular Function	Metalloendopeptidase Activity Peptidase Activity Metallopeptidase Activity Hydrolase Activity Metal Ion Binding	Chromatin Binding Protein Serine/threonine Kinase Activity Protein Binding Protein-macromolecule Adaptor Activity Histone Binding Histone H4K12ac Reader Activity Histone H4K5ac Reader Activity Histone H3K14ac Reader Activity Acetylation-dependent Protein Binding
	Biological Process	Respiratory System Process Proteolysis Neuropeptide Signaling Pathway Protein Processing	Neural Tube Closure Chromatin Organization Nucleosome Assembly Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Surface Receptor Signaling Pathway Via JAK-STAT Spermatogenesis Regulation Of Gene Expression Protein Localization To Chromatin T-helper 17 Cell Lineage Commitment Chromatin Looping Positive Regulation Of T-helper 17 Cell Lineage Commitment
Pathways			RUNX3 regulates p14-ARF
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 28008999) Feeling nervous ( 29500382) Hemoglobin levels ( 32327693) Inflammatory bowel disease ( 28008999) Ulcerative colitis ( 28008999)
Interacting Genes		1 interacting genes: USP19	8 interacting genes: E2F1 E2F2 H2BC26 H4C16 MECOM PKNOX1 SPOP TOP1
Entrez ID		9427	6046
HPRD ID		07066	03326
Ensembl ID		ENSG00000171551	ENSG00000204256
Uniprot IDs		A0A6F7YIA8 O95672	A0A1U9X7A8 E9PIQ3 P25440 X5CF57
PDB IDs			1X0J 2DVQ 2DVR 2DVS 2DVV 2E3K 2G4A 2YDW 2YEK 3AQA 3ONI 4A9E 4A9F 4A9H 4A9I 4A9J 4A9M 4A9N 4A9O 4AKN 4ALG 4ALH 4J1P 4MR5 4MR6 4QEU 4QEV 4QEW 4UYF 4UYG 4UYH 5BT5 5DFB 5DFC 5DFD 5DW1 5EK9 5HEL 5HEM 5HEN 5HFQ 5IBN 5IG6 5N2L 5O38 5O39 5O3A 5O3B 5O3C 5O3D 5O3E 5O3F 5O3G 5O3H 5O3I 5S9O 5U5S 5U6V 5UEW 5XHE 5XHK 6CUI 6DB0 6DBC 6DDI 6DDJ 6E6J 6FFE 6FFF 6FFG 6I80 6I81 6JKE 6K04 6K05 6MO7 6MO8 6MO9 6MOA 6ONY 6SWO 6SWP 6TQ1 6TQ2 6U61 6U71 6U8H 6ULQ 6ULT 6VIY 6WWB 6YTM 6Z7F 6Z8P 6ZB0 6ZB1 6ZB2 7DPN 7DPO 7ENV 7ENZ 7EO5 7JX7 7L6D 7L9G 7L9J 7L9K 7LAK 7NPY 7NPZ 7NQ0 7NQ1 7NQ2 7NQ3 7NQ5 7NQ7 7NQ8 7NQ9 7NQI 7NQJ 7OE4 7OE5 7OE6 7OE8 7OE9 7OEP 7OER 7OES 7OET 7OGY 7Q5O 7USG 7USH 7USI 7UU0 7VRH 7VRI 7VRK 7VRM 7VRO 7VRQ 7VRZ 7VS0 7VS1 7VSF 7WLN 7WMQ 7WMU 7WN5 7WNA 7WNI 8B5G 8B5H 8B5I 8B5J 8CV7 8DNQ 8PX2 8PX8 8SB6 8WYG 8Z69 9FBX
Enriched GO Terms of Interacting Partners?		Histone H4K5ac Reader Activity Histone H4K12ac Reader Activity Acetylation-dependent Protein Binding Histone H3K14ac Reader Activity Negative Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Cell Fate Commitment T-helper 17 Cell Lineage Commitment Positive Regulation Of T-helper 17 Cell Differentiation Positive Regulation Of T-helper 17 Cell Lineage Commitment Negative Regulation Of Muscle Organ Development Negative Regulation Of Muscle Tissue Development Negative Regulation Of Striated Muscle Tissue Development T-helper Cell Lineage Commitment CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment Alpha-beta T Cell Lineage Commitment Positive Regulation Of T-helper 17 Type Immune Response CD4-positive, Alpha-beta T Cell Lineage Commitment Chromatin Looping Regulation Of Cellular Response To Hypoxia Regulation Of ERAD Pathway Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of T-helper Cell Differentiation Regulation Of T-helper 17 Cell Differentiation T Cell Lineage Commitment Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Regulation Of T-helper 17 Type Immune Response Regulation Of Striated Muscle Tissue Development Hsp90 Protein Binding Regulation Of Cell Fate Commitment Regulation Of Muscle Organ Development Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation Regulation Of T-helper Cell Differentiation Protein Localization To Chromatin Positive Regulation Of Alpha-beta T Cell Differentiation Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Alpha-beta T Cell Activation Cell Surface Receptor Signaling Pathway Via STAT Regulation Of CD4-positive, Alpha-beta T Cell Activation Neural Tube Closure Tube Closure Regulation Of Response To Endoplasmic Reticulum Stress Cysteine-type Deubiquitinase Activity ERAD Pathway Protein Deubiquitination	Lens Fiber Cell Apoptotic Process Rb-E2F Complex DNA Binding
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