MYOCD and MYOD1

Number of citations of the paper that reports this interaction (PMID 17940050)
22

Data Source:
BioGRID (pull down)

		MYOCD	MYOD1
Gene Name		myocardin	myogenic differentiation 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Myofibril
	Molecular Function	Core Promoter Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Transcription Coactivator Activity Protein Binding Transcription Factor Binding Histone Acetyltransferase Binding Histone Deacetylase Binding R-SMAD Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Core Promoter Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding Nuclear Hormone Receptor Binding Protein Heterodimerization Activity E-box Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Growth By Extracellular Stimulus Vasculogenesis Response To Hypoxia Cardiac Ventricle Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Myotube Differentiation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cardiocyte Differentiation Regulation Of Histone Acetylation Hepatic Stellate Cell Activation Positive Regulation Of DNA Binding Cellular Component Maintenance Regulation Of Myoblast Differentiation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Smooth Muscle Contraction Lung Alveolus Development Digestive Tract Development Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Smooth Muscle Cell Differentiation Regulation Of Smooth Muscle Cell Differentiation Positive Regulation Of Smooth Muscle Cell Differentiation Cardiac Muscle Cell Differentiation Ventricular Cardiac Muscle Cell Differentiation Uterus Development Urinary Bladder Development Cell Growth Involved In Cardiac Muscle Cell Development Cellular Response To Growth Factor Stimulus Cellular Response To Hypoxia Ductus Arteriosus Closure Negative Regulation Of Beta-amyloid Clearance Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Smooth Muscle Cell Differentiation Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation Positive Regulation Of Cardiac Muscle Cell Differentiation Negative Regulation Of Skeletal Muscle Cell Differentiation	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Protein Phosphorylation Muscle Organ Development Myoblast Fate Determination Skeletal Muscle Tissue Development Cellular Response To Starvation Myotube Cell Development Myotube Differentiation Involved In Skeletal Muscle Regeneration Skeletal Muscle Cell Differentiation Muscle Cell Differentiation Muscle Cell Fate Commitment Positive Regulation Of Skeletal Muscle Tissue Regeneration Regulation Of RNA Splicing Skeletal Muscle Fiber Adaptation Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Muscle Cell Differentiation Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Oxygen Levels Positive Regulation Of Myoblast Fusion
Pathways			CDO in myogenesis Myogenesis
Drugs
Diseases
GWAS		Testosterone levels ( 22675492)
Protein-Protein Interactions		12 interactors: GOPC GSK3B KDM3A MAMSTR MKL1 MYOD1 SMAD2 SMAD3 SMARCA4 SRF STUB1 UBC	61 interactors: ASCL3 BHLHA15 BHLHE40 BHLHE41 C2orf88 CALM1 CALM2 CALM3 CARM1 CDC34 CDK2 CDK4 CDKN1C CIB2 CREBBP CSRP3 ELSPBP1 EP300 HAND1 HDAC1 HEY1 HIST1H3A HSP90AA1 ID1 ID2 ID3 ID4 IFRD1 JUN KAT2B KAT5 KPNA3 MDFI MEF2A MEF2C MOS MYOCD NCOR1 NCOR2 NR2F2 PHB2 POLR2G PRKCA PRMT5 PSMD4 PSME2 RB1 RORA RUNX1 RXRA SETD3 SMAD3 SMAD4 SMAD7 SP1 SRF STAT3 SUV39H1 TCF3 TCF4 TWIST1
Entrez ID		93649	4654
HPRD ID		09362	01166
Ensembl ID		ENSG00000141052	ENSG00000129152
Uniprot IDs		Q6N065 Q8IZQ8	P15172
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Negative Regulation Of Signaling Regulation Of Cellular Component Organization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Regulation Of Binding Transcription, DNA-templated Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Developmental Growth RNA Biosynthetic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Signal Transduction Muscle Cell Differentiation Cellular Nitrogen Compound Metabolic Process Cell Development Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Differentiation Response To Transforming Growth Factor Beta Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Stem Cell Differentiation Regulation Of RNA Biosynthetic Process RNA Metabolic Process Growth Regulation Of RNA Metabolic Process Smooth Muscle Cell Differentiation Positive Regulation Of Cell Development Regulation Of Gene Expression, Epigenetic Muscle Structure Development Primary MiRNA Processing Regulation Of Cell Differentiation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Gene Expression RNA Biosynthetic Process Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Rhythmic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Organ Development Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Anatomical Structure Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Organic Substance Organ Morphogenesis Anatomical Structure Development Cardiovascular System Development Regulation Of Cell Differentiation Heart Development Response To Growth Factor Biosynthetic Process Regulation Of Cell Cycle Developmental Process Cell Differentiation System Development Regulation Of Binding
Tagcloud ?		adaptation associate cardiac cardioenriched circuits close coactivators cofactors correlate directing discovered discuss entertained focus growing identifies inputs modulation mrtf networks nevertheless overlapping participate precise preclinical putative regulatory understand	antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed
Tagcloud (Difference) ?		adaptation associate cardiac cardioenriched circuits close coactivators cofactors correlate directing discovered discuss entertained focus growing identifies inputs modulation mrtf networks nevertheless overlapping participate precise preclinical putative regulatory understand	antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed
Tagcloud (Intersection) ?