MYOCD

Description		myocardin
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	Transcription Coactivator Activity Protein Binding Histone Acetyltransferase Binding Histone Deacetylase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding R-SMAD Binding DNA-binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Growth By Extracellular Stimulus Vasculogenesis Response To Hypoxia Cardiac Ventricle Development Chromatin Organization Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Heart Development Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Myotube Differentiation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cardiocyte Differentiation Vascular Associated Smooth Muscle Cell Differentiation Cellular Component Maintenance Regulation Of Myoblast Differentiation Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Smooth Muscle Contraction Lung Alveolus Development Digestive Tract Development Smooth Muscle Cell Differentiation Regulation Of Muscle Cell Differentiation Regulation Of Smooth Muscle Cell Differentiation Positive Regulation Of Smooth Muscle Cell Differentiation Cardiac Muscle Cell Differentiation Ventricular Cardiac Muscle Cell Differentiation Uterus Development Urinary Bladder Development Negative Regulation Of Cell Adhesion Molecule Production Cardiac Muscle Cell Myoblast Differentiation Cardiac Vascular Smooth Muscle Cell Differentiation Ductus Arteriosus Closure Negative Regulation Of Amyloid-beta Clearance Regulation Of Phenotypic Switching Positive Regulation Of MiRNA Transcription Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Positive Regulation Of Cardiac Muscle Cell Differentiation Negative Regulation Of Skeletal Muscle Cell Differentiation
Pathways		Cardiogenesis
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015 30061737) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483) PR interval ( 30046033 30679814 32439900) QRS duration ( 31251759) Systolic blood pressure change trajectory ( 27980656) Testosterone levels ( 22675492)
Novel Interacting Genes		1 novel interacting genes: NFATC3
Interacting Genes		11 interacting genes: GOPC GSK3B KDM3A MAMSTR MRTFA MYOD1 SMAD2 SMAD3 SMARCA4 SRF STUB1
Entrez ID		93649
HPRD ID		09362
Ensembl ID		ENSG00000141052
Uniprot IDs		Q8IZQ8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MiRNA Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of MiRNA Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of MiRNA Transcription Positive Regulation Of Macromolecule Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of MiRNA Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cis-regulatory Region Sequence-specific DNA Binding Chromatin DNA Binding Chromatin Binding Positive Regulation Of Biosynthetic Process Positive Regulation Of Developmental Process Positive Regulation Of Cell Differentiation R-SMAD Binding Negative Regulation Of MiRNA Transcription Ubiquitin Protein Ligase Binding Paraxial Mesoderm Morphogenesis Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Regulation Of Developmental Process Regulation Of Muscle Cell Differentiation Tau Protein Binding Mesoderm Formation Regulation Of RNA Metabolic Process Gastrulation Mesoderm Morphogenesis DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Pericardium Development Regulation Of Primary Metabolic Process Formation Of Primary Germ Layer SMAD Protein Complex Trophoblast Cell Migration Regulation Of Nucleobase-containing Compound Metabolic Process Heteromeric SMAD Protein Complex Nucleoplasm Transcription Regulator Complex Embryonic Foregut Morphogenesis Regulation Of Macromolecule Metabolic Process Nodal Signaling Pathway Co-SMAD Binding Positive Thymic T Cell Selection
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