TRMT10A and TRIM7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRMT10A	TRIM7
Description		tRNA methyltransferase 10A	tripartite motif containing 7
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Actin Cytoskeleton Extracellular Exosome	Nucleus Cytoplasm Golgi Apparatus
	Molecular Function	TRNA Binding RNA Binding Protein Binding Methyltransferase Activity Transferase Activity TRNA (guanosine(9)-N1)-methyltransferase Activity	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	TRNA N1-guanine Methylation TRNA Methylation Methylation	Protein Ubiquitination Innate Immune Response Defense Response To Virus Antiviral Innate Immune Response
Pathways		tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS
Interacting Genes		1 interacting genes: TRIM7	30 interacting genes: AQP1 ATG7 BCAM CDK13 CFL2 CRYGC CTNNAL1 DES GTF2A2 GYG1 IRAK4 MAD2L2 NAA35 NABP1 OTUD6A RAB2A RIN1 RNASE1 RNF187 RSPH14 SIAH1 SRC TP53I13 TRMT10A UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2N UBE2W
Entrez ID		93587	81786
HPRD ID		15241	11648
Ensembl ID		ENSG00000145331	ENSG00000146054
Uniprot IDs		Q8TBZ6 V9HVY8	Q9C029
PDB IDs		4FMW	6UMA 6UMB 7OVX 7OW2 7W0Q 7W0S 7W0T 7X6Y 7X6Z 7X70 7Y3A 7Y3B 7Y3C 8A5L 8A5M 8A8X 8R5B 8R5C 8R5D 9HIN
Enriched GO Terms of Interacting Partners?			Ubiquitin Conjugating Enzyme Activity Ubiquitin-protein Transferase Activity Post-translational Protein Modification Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein Polyubiquitination Protein K48-linked Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Transferase Activity Protein Monoubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process TORC1 Signaling Negative Regulation Of TORC1 Signaling Protein Ubiquitination TOR Signaling Proteasomal Protein Catabolic Process Negative Regulation Of TOR Signaling Proteolysis Regulation Of TORC1 Signaling Macromolecule Catabolic Process Protein Modification Process Cytosol Protein Catabolic Process Cellular Response To Nutrient Levels Regulation Of TOR Signaling Catabolic Process Protein Autoubiquitination Nucleus Ubiquitin Protein Ligase Activity Extracellular Exosome ATP Binding Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Polyubiquitination Nucleotide Binding Intracellular Signal Transduction Protein Binding Endolysosomal Toll-like Receptor Signaling Pathway Macromolecule Metabolic Process Ephrin Receptor Binding Regulation Of Protein Polyubiquitination Ficolin-1-rich Granule Lumen Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Supramolecular Fiber Organization Defense Response To Virus Response To Nutrient Levels Postreplication Repair
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