ERMAP and LEMD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ERMAP	LEMD1
Description		erythroblast membrane associated protein (Scianna blood group)	LEM domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane External Side Of Plasma Membrane Membrane	Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding	Protein Binding
	Biological Process	Regulation Of Cytokine Production T Cell Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Red cell distribution width ( 32888494) Visceral fat ( 30942860)	Ceramide levels (C22:0) ( 32489964) Ceramide levels (C24:0) ( 32489964) Sleep (1/3-day periodicity) ( 33075057)
Interacting Genes		6 interacting genes: CFTR EMD KRTAP3-3 LEMD1 TMEM14A VASP	13 interacting genes: AQP6 BLCAP EBP ERMAP JAGN1 MEOX2 MGST3 REEP4 RETREG3 SCN3B SLC16A7 TMPPE ZDHHC15
Entrez ID		114625	93273
HPRD ID		12355	13983
Ensembl ID		ENSG00000164010	ENSG00000186007
Uniprot IDs		A0A1C9HIH9 Q96PL5	Q68G75
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding TMEM240-body Positive Regulation Of Anion Channel Activity Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Cortical Endoplasmic Reticulum Amelogenesis Positive Regulation Of Protein Transport ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Profilin Binding	Endoplasmic Reticulum Organization Membrane Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Nitrate Transmembrane Transporter Activity Endoplasmic Reticulum Membrane Endoplasmic Reticulum Pyruvate Secondary Active Transmembrane Transporter Activity Cholesterol-5,6-oxide Hydrolase Activity PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Secondary Active Monocarboxylate Transmembrane Transporter Activity C-8 Sterol Isomerase Activity Cholestenol Delta-isomerase Activity
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