PIGM and PIGX

Number of citations of the paper that reports this interaction (PMID 15635094)
10

Data Source:
HPRD (in vivo, in vitro)

		PIGM	PIGX
Gene Name		phosphatidylinositol glycan anchor biosynthesis, class M	phosphatidylinositol glycan anchor biosynthesis, class X
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Mannosyltransferase Activity
	Biological Process	C-terminal Protein Lipidation Preassembly Of GPI Anchor In ER Membrane Post-translational Protein Modification Cellular Protein Metabolic Process Mannosylation	C-terminal Protein Lipidation Preassembly Of GPI Anchor In ER Membrane Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Synthesis of glycosylphosphatidylinositol (GPI) Post-translational protein modification Post-translational modification: synthesis of GPI-anchored proteins	Synthesis of glycosylphosphatidylinositol (GPI) Post-translational protein modification Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: CHEK1 PIGX	1 interactors: PIGM
Entrez ID		93183	54965
HPRD ID		15133	07921
Ensembl ID		ENSG00000143315	ENSG00000163964
Uniprot IDs		Q9H3S5	B4DFZ9 Q8TBF5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Histone H3-T11 Phosphorylation Regulation Of Mitotic Centrosome Separation Chromatin-mediated Maintenance Of Transcription Cellular Response To Caffeine Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Histone H3-K9 Acetylation DNA Damage Induced Protein Phosphorylation Negative Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Gene Expression, Epigenetic Preassembly Of GPI Anchor In ER Membrane Replicative Senescence Negative Regulation Of DNA Biosynthetic Process Response To Caffeine Regulation Of Double-strand Break Repair C-terminal Protein Lipidation G2 DNA Damage Checkpoint Cellular Response To Alkaloid Histone Phosphorylation Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of DNA Biosynthetic Process Peptidyl-threonine Phosphorylation Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Histone Acetylation Regulation Of Centrosome Cycle Negative Regulation Of Mitotic Nuclear Division Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress GPI Anchor Biosynthetic Process Cellular Response To UV GPI Anchor Metabolic Process Regulation Of DNA Repair Regulation Of DNA Recombination Cell Aging Cellular Response To Mechanical Stimulus Negative Regulation Of Cell Division Glycolipid Biosynthetic Process Cellular Response To Light Stimulus Negative Regulation Of DNA Metabolic Process Protein Lipidation Lipoprotein Biosynthetic Process G2/M Transition Of Mitotic Cell Cycle Phosphatidylinositol Biosynthetic Process Regulation Of Histone Modification Regulation Of Mitotic Nuclear Division Regulation Of Response To DNA Damage Stimulus Response To UV Glycolipid Metabolic Process Cellular Response To Radiation	Preassembly Of GPI Anchor In ER Membrane C-terminal Protein Lipidation Mannosylation GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process Post-translational Protein Modification Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycosylation Glycerolipid Metabolic Process Phospholipid Metabolic Process Lipid Biosynthetic Process
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