PIGM

Description		phosphatidylinositol glycan anchor biosynthesis class M
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Glycosylphosphatidylinositol-mannosyltransferase I Complex
	Molecular Function	Mannosyltransferase Activity GPI Mannosyltransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity Alpha-1,4-mannosyltransferase Activity Dol-P-Man:GlcN-acyl-PI Alpha-1,4-mannosyltransferase Activity
	Biological Process	GPI Anchor Biosynthetic Process
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases		Glycosylphosphatidylinositol (GPI) deficiency
GWAS		Bipolar disorder ( 31043756)
Interacting Genes		3 interacting genes: CHEK1 LTB4R2 PIGX
Entrez ID		93183
HPRD ID		15133
Ensembl ID		ENSG00000143315
Uniprot IDs		Q9H3S5
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of G0 To G1 Transition Histone H3T11 Kinase Activity Regulation Of Mitotic Centrosome Separation Leukotriene Signaling Pathway Keratinocyte Migration Leukotriene B4 Receptor Activity Leukotriene Receptor Activity Mitotic Nuclear Membrane Disassembly Negative Regulation Of Adenylate Cyclase Activity Membrane Disassembly Nuclear Membrane Disassembly Inner Cell Mass Cell Proliferation Replicative Senescence Replication Fork Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Peptidyl-threonine Phosphorylation Nuclear Envelope Organization GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Apoptotic Process Involved In Development Positive Regulation Of Cell Cycle G2/M Phase Transition Mitotic G2 DNA Damage Checkpoint Signaling Epithelial Cell Migration
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