TMEM259 and ARSL

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		TMEM259	ARSL
Name		transmembrane protein 259	arylsulfatase L
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Endoplasmic Reticulum Lumen Golgi Apparatus Golgi Stack Extracellular Exosome
	Molecular Function	None	Arylsulfatase Activity Hydrolase Activity Metal Ion Binding
	Biological Process	Response To Endoplasmic Reticulum Stress Positive Regulation Of ERAD Pathway	Skeletal System Development
Pathways		None	The activation of arylsulfatases Glycosphingolipid catabolism
GWAS		Eosinophil percentage of granulocytes ( 27863252 ) Red cell distribution width ( 27863252 )	No GWAS studies recorded
Interacting Genes		2 interacting genes: ADRB2 ARSL	4 interacting genes: COQ6 NDN TMEM259 TNK2
Entrez ID		91304	415
HPRD ID		12710	02171
Ensembl ID		ENSG00000182087	ENSG00000157399
Uniprot IDs		B3KTL0 Q4ZIN3	A0A5F9ZHX8 A0A804HJF6 A1L484 B7Z1M0 B7Z6V4 F5GYY5 F5H324 P51690
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Response To Psychosocial Stress Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Norepinephrine Binding Positive Regulation Of Lipophagy AMPA Selective Glutamate Receptor Signaling Pathway Beta2-adrenergic Receptor Activity Positive Regulation Of Autophagosome Maturation Heat Generation Diet Induced Thermogenesis Adrenergic Receptor Activity Arylsulfatase Activity Adenylate Cyclase Binding Negative Regulation Of Smooth Muscle Contraction Negative Regulation Of Multicellular Organism Growth Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Autophagosome Maturation Positive Regulation Of CAMP/PKA Signal Transduction Negative Regulation Of Muscle Contraction Neuronal Dense Core Vesicle Adrenergic Receptor Signaling Pathway Negative Regulation Of Systemic Arterial Blood Pressure Detection Of Light Stimulus Involved In Visual Perception Adaptive Thermogenesis Bone Resorption Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Brown Fat Cell Differentiation Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Excitatory Postsynaptic Potential Temperature Homeostasis Positive Regulation Of Protein-containing Complex Disassembly Clathrin-coated Vesicle Membrane Golgi Stack Regulation Of CAMP/PKA Signal Transduction Potassium Channel Regulator Activity Ligand-gated Ion Channel Signaling Pathway Regulation Of Systemic Arterial Blood Pressure Response To Cold Positive Regulation Of Bone Mineralization Smooth Muscle Contraction Vasodilation Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Glutamate Receptor Signaling Pathway Cellular Response To Amyloid-beta Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Ossification Endosome To Lysosome Transport Negative Regulation Of Blood Pressure	4-hydroxy-3-all-trans-polyprenylbenzoate Oxygenase Activity 2-methoxy-6-polyprenolphenol 4-hydroxylase Activity Grb2-EGFR Complex Cytoophidium