SYT16 and SDR16C5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SYT16	SDR16C5
Description		synaptotagmin 16	short chain dehydrogenase/reductase family 16C member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Plasma Membrane Membrane Transcription Repressor Complex
	Molecular Function	Protein Binding Phospholipid Binding Identical Protein Binding	Transcription Corepressor Activity All-trans-retinol Dehydrogenase (NAD+) Activity Protein Binding Oxidoreductase Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Retinol Metabolic Process Retinal Metabolic Process Keratinocyte Proliferation Negative Regulation Of Gene Expression, Epigenetic
Pathways			RA biosynthesis pathway
Drugs
Diseases
GWAS		Adult body size ( 32376654) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Chronotype ( 30696823) Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136) Hepatitis ( 25705159) Longevity (90 years and older) ( 24688116) Recurrence of mild malaria attacks ( 31667592) Self-rated health ( 20707712) Telomere length ( 24478790)	Height ( 20881960 28552196 31562340) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278)
Interacting Genes		29 interacting genes: AGTRAP APOC1 APOC2 APOC4 C10orf67 CMTM5 CYSTM1 DERL3 FGF14 GSG1 HIGD1C LDAF1 MPC2 MTFR1 NCOA5 PHC2 PLEKHF2 RABAC1 REEP6 RER1 RHBDD2 RPRM RTN4 SDR16C5 SFT2D1 SYT14 TMEM239 TVP23B ZBTB14	12 interacting genes: EHHADH EXTL1 FUNDC2 GAD2 HSFX1 HSFX2 NDRG4 NLK SENP2 SNX1 SYT16 TTPA
Entrez ID		83851	195814
HPRD ID		15461	12351
Ensembl ID		ENSG00000139973	ENSG00000170786
Uniprot IDs		Q17RD7	B3KT84 G3V145 Q8N3Y7
PDB IDs
Enriched GO Terms of Interacting Partners?		High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Acylglycerol Homeostasis Triglyceride Homeostasis Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Signal Recognition Particle Binding Endoplasmic Reticulum Lipid Homeostasis Chylomicron Phospholipid Efflux Endoplasmic Reticulum Membrane Negative Regulation Of Lipoprotein Particle Clearance Negative Regulation Of Cholesterol Transport Plasma Lipoprotein Particle Clearance Lipoprotein Metabolic Process Regulation Of Phospholipid Metabolic Process Cholesterol Efflux Plasma Lipoprotein Particle Remodeling Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Phosphatidylcholine Catabolic Process Membrane Negative Regulation Of Vasculogenesis Positive Regulation Of ERBB3 Signaling Pathway Cell Adhesion Involved In Sprouting Angiogenesis Protein-containing Complex Remodeling Negative Regulation Of Lipid Transport Regulation Of Triglyceride Metabolic Process
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