MGME1 and MAGEA11

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MGME1	MAGEA11
Description		mitochondrial genome maintenance exonuclease 1	MAGE family member A11
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body
	Molecular Function	Nuclease Activity Exonuclease Activity Protein Binding Single-stranded DNA Exodeoxyribonuclease Activity Hydrolase Activity 5'-flap Endonuclease Activity Single-stranded DNA 5'-3' DNA Exonuclease Activity	Protein Binding Histone Deacetylase Binding
	Biological Process	Mitochondrial DNA Replication DNA Repair DNA Damage Response Mitochondrial DNA Repair	Negative Regulation Of Transcription By RNA Polymerase II
Pathways		Strand-asynchronous mitochondrial DNA replication
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: MAGEA11 PICK1	115 interacting genes: ACMSD ACSM2B ACTN1 AKR1C3 ALDH5A1 AR ARHGAP29 BCL2L11 BEX2 BIRC2 BRD1 C18orf54 C22orf39 CASP7 CAVIN3 CCDC106 CCDC14 CCDC146 CCDC185 CCDC27 CCNA2 CDC20B CDKN2B CEP76 CLUAP1 CORO1A COX7A2L CSNK2A1 CTTNBP2 DLGAP1 DNAJC10 DOCK10 ENOX2 EWSR1 FAM156A FAM161A FBXO46 GADD45GIP1 GCSH GNPDA1 HOXB5 IFI44 IL11 IL6ST ILF3 JADE3 KIAA0408 LMBR1L LNX1 MAPK3 MCRS1 MED28 MGME1 MLF1 MTA1 MXD3 MYOZ1 NCOA2 NDEL1 NDUFAF1 NDUFB9 NIF3L1 NOL4 NOS3 NSUN4 NTAQ1 OTUB2 PCBD2 PCF11 PDE4B PHYH PIK3IP1 PIN4 PLCXD3 PNKD PNKP POLR1D PPIF PPM1K PRDX3 PRKRIP1 PSMF1 RADIL RANBP10 RBM23 REX1BD SH2D4A SNX20 SNX7 SPMIP9 STAR SUCLA2 SUOX SUV39H2 TCEA2 TCEANC TCF25 TEKTL1 THEM5 TMEM123 TPM3 TRIM27 TRIM51 TRMT1 TXN2 UBE2D4 UBE3D USP20 UTP25 VTA1 WTAP ZBTB16 ZCCHC12 ZNF655 ZSWIM2
Entrez ID		92667	4110
HPRD ID		12783	02281
Ensembl ID		ENSG00000125871	ENSG00000185247
Uniprot IDs		Q5QPE7 Q5QPE8 Q9BQP7	G5E962 P43364
PDB IDs		5ZYT 5ZYU 5ZYV 5ZYW 8XA9	6WJH
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Membrane Curvature Sensor Activity Negative Regulation Of Actin Nucleation Neuronal Ion Channel Clustering Dendritic Spine Maintenance Arp2/3 Complex Binding Long-term Synaptic Depression	Mitochondrial Matrix Protein Binding Mitochondrion Catabolic Process
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