MOB1B and NT5C2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MOB1B	NT5C2
Gene Name		MOB kinase activator 1B	5-nucleotidase, cytosolic II
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome	Cytosol
	Molecular Function	Protein Binding Kinase Activator Activity Kinase Binding Metal Ion Binding	Nucleotide Binding Protein Binding 5'-nucleotidase Activity Metal Ion Binding Nucleoside Phosphotransferase Activity
	Biological Process	Hippo Signaling Positive Regulation Of Phosphorylation Protein Autophosphorylation	Purine Nucleobase Metabolic Process Purine Nucleotide Catabolic Process Phosphorylation Dephosphorylation Drug Metabolic Process Small Molecule Metabolic Process IMP Metabolic Process Adenosine Metabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways		Signaling by Hippo	Purine catabolism Purine metabolism Metabolism of nucleotides Abacavir transport and metabolism Abacavir metabolism
Drugs			Adenosine triphosphate Ribavirin
Diseases
GWAS			Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Blood pressure ( 21572416 21909110) Coronary heart disease ( 21378990) Schizophrenia ( 21926974 22688191 23894747) Systolic blood pressure ( 19430483 21909115)
Protein-Protein Interactions		4 interactors: APP CCDC53 NT5C2 TNIP1	10 interactors: ATP5O CALM1 FXR2 MOB1B MOB3B MOB3C NME7 NOC4L NUDT18 SDCBP
Entrez ID		92597	22978
HPRD ID		17582	02686
Ensembl ID		ENSG00000173542	ENSG00000076685
Uniprot IDs		B3KSH6 Q7L9L4	A8K6K2 B7Z382 P49902
PDB IDs			2J2C 2JC9 2JCM 2XCV 2XCW 2XCX 2XJB 2XJC 2XJD 2XJE 2XJF 4H4B
Enriched GO Terms of Interacting Partners?		Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling	Purine Nucleoside Metabolic Process Ribonucleotide Metabolic Process Nucleoside Metabolic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Nucleoside Diphosphate Metabolic Process Organophosphate Metabolic Process Nucleoside Triphosphate Biosynthetic Process GDP Catabolic Process DGDP Catabolic Process DADP Catabolic Process Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Phosphate-containing Compound Metabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Regulation Of High Voltage-gated Calcium Channel Activity Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Regulation Of Extracellular Vesicular Exosome Assembly Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Membrane Organization Positive Regulation Of Phosphorylation Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Ribonucleoside Diphosphate Catabolic Process Establishment Of Localization In Cell Nucleoside Diphosphate Catabolic Process Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Deoxyribonucleoside Diphosphate Metabolic Process Detection Of Calcium Ion Substrate-dependent Cell Migration, Cell Extension Energy Derivation By Oxidation Of Organic Compounds Nucleotide Biosynthetic Process Purine Ribonucleoside Catabolic Process Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Small Molecule Metabolic Process Cellular Localization Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Mitochondrial ATP Synthesis Coupled Proton Transport Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Tagcloud ?		1a binder centrosomes delta embryogenesis exert hippo homozygous hyperplastic hyperproliferation inactivated kdko keratinocyte keratinocytes lats malnutrition mob1a mps overlapping renewal resembled soon suppressors tamoxifen tr trichilemmal yap1	atp2b1 atxn2 bdkrb2 cacnb2 csk cyp171a cyp17a1 cyp1a2 eh gwas hfe jan meant mthfr nppa nppb overlapped pharmacogenomics plcd3 plekha7 sh2b3 stk39 tbx3 tbx5 ulk3 ulk4 umod wnk4 znf652
Tagcloud (Difference) ?		1a binder centrosomes delta embryogenesis exert hippo homozygous hyperplastic hyperproliferation inactivated kdko keratinocyte keratinocytes lats malnutrition mob1a mps overlapping renewal resembled soon suppressors tamoxifen tr trichilemmal yap1	atp2b1 atxn2 bdkrb2 cacnb2 csk cyp171a cyp17a1 cyp1a2 eh gwas hfe jan meant mthfr nppa nppb overlapped pharmacogenomics plcd3 plekha7 sh2b3 stk39 tbx3 tbx5 ulk3 ulk4 umod wnk4 znf652
Tagcloud (Intersection) ?