GPR50 and ZNF572

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		GPR50	ZNF572
Description		G protein-coupled receptor 50	zinc finger protein 572
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Plasma Membrane Postsynaptic Density Membrane Synapse	Nucleus Nucleoplasm
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Melatonin Receptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process
Pathways
Drugs
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		4 interacting genes: ARRB1 MTNR1A MTNR1B ZNF572	60 interacting genes: ATOSB BEGAIN BOLA1 CADPS CARD9 CBY2 CCDC102B CCDC136 CCDC33 CDR2L CEP57L1 CEP70 CPNE7 DEUP1 DRC4 FSD2 GOLGA2 GPR50 HAP1 HOOK1 HOOK2 IL16 KATNBL1 KIF9 KIFC3 KLC3 KRT31 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 LZTS1 LZTS2 MDFI MEOX2 MLLT3 MTUS2 NDEL1 PRPH REL SPAG5 TFIP11 TRAF1 TRAF2 TRIM27 TRIM54 VIM WTAP YJU2B ZBTB1 ZBTB8A ZNF165 ZNF250 ZNF383 ZNF417 ZNF57 ZNF774 ZNF835
Entrez ID		9248	137209
HPRD ID		02194	15851
Ensembl ID		ENSG00000102195	ENSG00000180938
Uniprot IDs		Q13585	Q7Z3I7
PDB IDs
Enriched GO Terms of Interacting Partners?		Melatonin Receptor Activity G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Angiotensin Receptor Binding Negative Adaptation Of Signaling Pathway Desensitization Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Neuronal Action Potential Negative Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Arrestin Family Protein Binding	Microtubule Binding Microtubule Intermediate Filament Keratin Filament Cytoskeleton Identical Protein Binding Microtubule-based Process Kinesin Complex Cytoskeleton-dependent Intracellular Transport Protein Binding Centrosome FHF Complex Microtubule Cytoskeleton Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Protein Localization To Perinuclear Region Of Cytoplasm Microtubule-based Movement Ciliary Rootlet Thioesterase Binding Establishment Of Vesicle Localization Vesicle Transport Along Microtubule Cytoskeleton Organization Vesicle Localization
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