C1orf105 and SBK3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C1orf105	SBK3
Description		chromosome 1 open reading frame 105	SH3 domain binding kinase family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Protein Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process
Pathways
Drugs			Fostamatinib
Diseases
GWAS		A body shape index ( 34021172) Daytime sleep phenotypes ( 27126917) Hemoglobin ( 32888494) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Immature fraction of reticulocytes ( 27863252 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet distribution width ( 27863252) Red cell distribution width ( 32888494 28957414 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 30389748 34021172)
Interacting Genes		7 interacting genes: APP ENKD1 FBXO7 MAPK9 POLR1C PSMA3 SBK3	13 interacting genes: AIMP2 ATXN7L2 C1orf105 CRY2 DMAP1 EXOSC2 GATAD2B MBD3L2 NOTO POLDIP3 SMAD3 SNRNP35 TNNT1
Entrez ID		92346	100130827
HPRD ID		14291
Ensembl ID		ENSG00000180999	ENSG00000231274
Uniprot IDs		O95561 Q5R3C7	P0C264
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Apoptotic Signaling Pathway Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization JUN Kinase Activity Protein Localization To Tricellular Tight Junction Lewy Body Core Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway
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