SBK3 and GATAD2B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SBK3	GATAD2B
Description		SH3 domain binding kinase family member 3	GATA zinc finger domain containing 2B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Chromosome NuRD Complex Nuclear Speck Protein-containing Complex
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Protein Binding Zinc Ion Binding Nucleosomal DNA Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Cell Fate Specification Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Regulation Of Stem Cell Differentiation
Pathways			HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Potential therapeutics for SARS Regulation of endogenous retroelements by KRAB-ZFP proteins Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Drugs		Fostamatinib
Diseases
GWAS			Age at first birth ( 27798627) Age at first sexual intercourse ( 34211149) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Empathy quotient ( 29527006) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) General cognitive ability ( 29844566) Height ( 31562340) Lentiform nucleus volume ( 22903471) Number of children ever born ( 27798627) Raw vegetable consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		13 interacting genes: AIMP2 ATXN7L2 C1orf105 CRY2 DMAP1 EXOSC2 GATAD2B MBD3L2 NOTO POLDIP3 SMAD3 SNRNP35 TNNT1	29 interacting genes: CALCOCO2 CDKN2D CEP70 ERCC6 FHL2 GOLGA2 GPSM3 H2AC20 H2BC21 H3C1 H4C1 KAT2B MBD2 MBD3 MTNR1A NGB NME7 NOXA1 PRKAB2 RBPMS RPGRIP1 SBK3 SMAD2 SUMO2 TEX11 TRAF1 TRIM27 USHBP1 ZGPAT
Entrez ID		100130827	57459
HPRD ID			15094
Ensembl ID		ENSG00000231274	ENSG00000143614
Uniprot IDs		P0C264	Q8WXI9
PDB IDs
Enriched GO Terms of Interacting Partners?			Chromatin Remodeling Chromatin Organization Epigenetic Regulation Of Gene Expression Chromosome Structural Constituent Of Chromatin Nucleosome Response To Bisphenol A Nucleoplasm Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Negative Regulation Of Gene Expression, Epigenetic Ventricular Cardiac Muscle Tissue Development NuRD Complex SUMO Transferase Activity
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