SBK3 and SNRNP35

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SBK3	SNRNP35
Description		SH3 domain binding kinase family member 3	small nuclear ribonucleoprotein U11/U12 subunit 35
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Nucleolus Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding SnRNA Binding
	Biological Process		MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			mRNA Splicing - Minor Pathway
Drugs		Fostamatinib
Diseases
GWAS			Educational attainment ( 25201988) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		13 interacting genes: AIMP2 ATXN7L2 C1orf105 CRY2 DMAP1 EXOSC2 GATAD2B MBD3L2 NOTO POLDIP3 SMAD3 SNRNP35 TNNT1	16 interacting genes: - ANKRD11 APP CCDC57 CKS1B CLK3 ILK MAP4K2 PLEKHF2 SBK3 SNAPC3 SRPK2 SYT17 TAB1 TNFSF11 U2AF1
Entrez ID		100130827	11066
HPRD ID			15595
Ensembl ID		ENSG00000231274	ENSG00000184209
Uniprot IDs		P0C264	Q16560
PDB IDs			8R7N 8Y6O 9GBW 9GBZ 9GCM
Enriched GO Terms of Interacting Partners?			Intracellular Signaling Cassette Positive Regulation Of JNK Cascade Protein Serine/threonine Kinase Activity Protein Kinase Activity Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
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