INTS4 and KIAA0513

Number of citations of the paper that reports this interaction (PMID 17010949)
2

Data Source:
HPRD (two hybrid)

		INTS4	KIAA0513
Gene Name		integrator complex subunit 4	KIAA0513
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integrator Complex	Cytoplasm
	Molecular Function	Protein Binding
	Biological Process	SnRNA Processing
Pathways
Drugs
Diseases
GWAS			Amyotrophic lateral sclerosis ( 22959728)
Protein-Protein Interactions		4 interactors: HGS KIAA0513 USHBP1 ZMIZ2	4 interactors: APP HAX1 INTS4 WWC1
Entrez ID		92105	9764
HPRD ID		12386	17192
Ensembl ID		ENSG00000149262	ENSG00000135709
Uniprot IDs		Q96HW7	B4DSS5 O60268
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Targeting To Lysosome Protein Localization To Lysosome Membrane Invagination Negative Regulation Of JAK-STAT Cascade Protein Targeting To Vacuole Establishment Of Protein Localization To Vacuole Endosome To Lysosome Transport Lysosomal Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Positive Regulation Of Gene Expression Positive Regulation Of Exocytosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vacuolar Transport Regulation Of ERBB Signaling Pathway Regulation Of JAK-STAT Cascade	Synaptic Growth At Neuromuscular Junction Regulation Of Peptidyl-tyrosine Phosphorylation Collateral Sprouting In Absence Of Injury Regulation Of Protein Targeting To Mitochondrion Regulation Of Phosphorylation Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Developmental Growth Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Hippo Signaling Regulation Of Phosphorus Metabolic Process Axon Choice Point Recognition Regulation Of Hippo Signaling Positive Regulation Of Granulocyte Differentiation Neuron Remodeling Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Mitochondrion Degradation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Intracellular Transport Positive Regulation Of Actin Cytoskeleton Reorganization Regulation Of Cellular Ketone Metabolic Process Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Regulation Of Growth Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Hippo Signaling Positive Regulation Of Cellular Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity SnRNA Processing Mating Behavior Regulation Of Signal Transduction Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Negative Regulation Of Organ Growth SnRNA Metabolic Process Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Intracellular Signal Transduction Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
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