INTS4 and KIAA0513

Number of citations of the paper that reports this interaction (PubMedID 17010949)
0

Data Source:
HPRD (two hybrid)

		INTS4	KIAA0513
Description		integrator complex subunit 4	KIAA0513
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Integrator Complex INTAC Complex	Cytoplasm
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	SnRNA Processing Regulation Of Transcription Elongation By RNA Polymerase II RNA Polymerase II Transcription Initiation Surveillance
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Platelet count ( 32888494) Tourette syndrome ( 30818990)	Amyotrophic lateral sclerosis ( 22959728) Dysphagia ( 26116289) Lateral ventricle temporal horn volume ( 31530798)
Interacting Genes		9 interacting genes: HGS KIAA0513 LHX3 MEIS3 PCM1 PYGM RNF10 USHBP1 ZMIZ2	4 interacting genes: APP HAX1 INTS4 WWC1
Entrez ID		92105	9764
HPRD ID		12386	17192
Ensembl ID		ENSG00000149262	ENSG00000135709
Uniprot IDs		A0A8C8UVZ7 A0A8Q3SHL8 A0A8Q3SHT4 A0A8Q3WKB5 Q96HW7	O60268
PDB IDs		7BFP 7BFQ 7CUN 7PKS 7YCX 8R2D 8RBX 8RBZ 8RC4 8YJB
Enriched GO Terms of Interacting Partners?			Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Regulation Of DNA-templated Transcription Regulation Of Type II Interferon Production Cell Activation Involved In Immune Response Amylin Binding Regulation Of RNA Biosynthetic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of RNA Metabolic Process Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Response To Peptide Positive Regulation Of Type II Interferon Production Positive Regulation Of Nucleobase-containing Compound Metabolic Process Response To Cytokine Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of DNA-templated Transcription Plasmacytoid Dendritic Cell Differentiation Signaling Adaptor Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Plasmacytoid Dendritic Cell Activation Follicular B Cell Differentiation Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Granulocyte Colony-stimulating Factor Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Gene Expression Regulation Of Spontaneous Synaptic Transmission Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II
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