FDXACB1 and TUBGCP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FDXACB1	TUBGCP4
Description		ferredoxin-fold anticodon binding domain containing 1	tubulin gamma complex component 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Spindle Pole Gamma-tubulin Complex Gamma-tubulin Ring Complex Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Microtubule Cytoskeleton Membrane Recycling Endosome
	Molecular Function	Protein Binding RRNA (uridine-N3-)-methyltransferase Activity	Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process	RRNA Base Methylation	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly
Pathways			Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS		Asthma or allergic disease (pleiotropy) ( 29785011)	Glycine levels ( 30837465) HDL cholesterol ( 30275531) Liver enzyme levels (alkaline phosphatase) ( 33972514) Triglycerides ( 30275531)
Interacting Genes		5 interacting genes: MYNN TRAF2 TUBGCP4 ZNF250 ZSCAN18	32 interacting genes: ADAMTSL4 AP2B1 CBY2 CCDC85B CHIC2 DGCR6 EFHC2 FBF1 FDXACB1 GFAP GLYCTK GOLGA2 KCTD17 KRT15 KRT18 KRT4 KRT6B LZTR1 MAD1L1 NUDT3 PAK5 PHKA1 RNF146 RPRD1B SDSL STN1 TRIM27 TRIM55 TRIM63 TUBG1 USHBP1 VIM
Entrez ID		91893	27229
HPRD ID		19366	10616
Ensembl ID		ENSG00000255561	ENSG00000137822
Uniprot IDs		Q9BRP7	Q9UGJ1
PDB IDs			3RIP 6V69 6V6S 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 7QJE 8Q62 8RX1 8VRD 8VRJ 8VRK
Enriched GO Terms of Interacting Partners?		Sphingolipid Binding TORC2 Complex Disassembly Zinc Ion Binding TRAF2-GSTP1 Complex IRE1-TRAF2-ASK1 Complex TORC1 Complex Assembly CD40 Receptor Binding Tumor Necrosis Factor Receptor Superfamily Complex Thioesterase Binding CD40 Receptor Complex CD40 Signaling Pathway Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of JUN Kinase Activity CD27 Signaling Pathway Tumor Necrosis Factor Binding Tumor Necrosis Factor Receptor Superfamily Binding Interleukin-17-mediated Signaling Pathway Gamma-tubulin Ring Complex Gamma-tubulin Complex DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of DNA-templated Transcription TORC2 Signaling Cellular Response To Nitric Oxide Regulation Of RNA Biosynthetic Process Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Mitogen-activated Protein Kinase Kinase Kinase Binding Microtubule Minus-end Binding Cellular Response To Reactive Nitrogen Species	Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Cytoskeleton Intermediate Filament Organization Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Cytoskeleton Organization Supramolecular Fiber Organization Cytoskeleton Identical Protein Binding Bergmann Glial Cell Differentiation Structural Constituent Of Skin Epidermis Scaffold Protein Binding Microtubule Astrocyte Development
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