ACY3 and ASPA

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)

		ACY3	ASPA
Description		aminoacylase 3	aspartoacylase
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane Apical Plasma Membrane Extracellular Exosome	Nucleus Cytoplasm Cytosol
	Molecular Function	Aminoacylase Activity Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Ester Bonds Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Identical Protein Binding Metal Ion Binding	Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Ester Bonds Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Aspartoacylase Activity Identical Protein Binding Metal Ion Binding
	Biological Process		Acetate Metabolic Process Aspartate Metabolic Process
Pathways		Aflatoxin activation and detoxification	Aspartate and asparagine metabolism
Drugs			Aspartic acid Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases			Canavan disease (CD)
GWAS		Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 24625756 33031748) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Waist circumference adjusted for body mass index ( 34021172)	Myopia (pathological) ( 23049088)
Interacting Genes		21 interacting genes: AAMDC ARF5 ASPA CYSRT1 DDIT4L GORASP2 INCA1 KRTAP10-3 KRTAP10-8 KRTAP15-1 KRTAP26-1 LNX1 MAP3K8 NEDD4L NOTCH2NLA PIAS2 PLEKHF2 PMM2 PTGER4 RARG RRAS	3 interacting genes: ACY3 DUSP29 HUNK
Entrez ID		91703	443
HPRD ID		12422	02033
Ensembl ID		ENSG00000132744	ENSG00000108381
Uniprot IDs		E9PRA7 Q96HD9	P45381 Q6FH48
PDB IDs			2I3C 2O4H 2O53 2Q51 4MRI 4MXU 4NFR 4TNU
Enriched GO Terms of Interacting Partners?		Intermediate Filament
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